Home History
| England League 1 | 2022/10/01 14:00 | Exeter v Bristol Rovers | D | 2-2 |
| England League 1 | 2022/09/24 11:30 | Forest Green v Exeter | W | 0-4 |
| England League 1 | 2022/09/17 14:00 | Exeter v Burton Albion | L | 0-2 |
| England League 1 | 2022/09/13 18:45 | Shrewsbury v Exeter | L | 3-2 |
| England League 1 | 2022/09/03 14:00 | Exeter v Milton Keynes Dons | W | 1-0 |
| England EFL Trophy | 2022/08/30 18:00 | Exeter v Newport County | L | 1-2 |
| England League 1 | 2022/08/27 14:00 | Accrington Stanley v Exeter | D | 0-0 |
| England EFL Cup | 2022/08/23 18:45 | Gillingham v Exeter | D | 0-0 |
Away History
| England Premier League 2 | 2022/09/16 18:00 | Leeds U21 v Southampton U21 | L | 6-2 |
| England EFL Trophy | 2022/08/30 18:00 | Forest Green v Southampton U21 | L | 3-1 |
| England Premier League 2 | 2022/08/26 18:00 | Southampton U21 v Norwich U21 | D | 1-1 |
| England Premier League 2 | 2022/08/19 18:00 | Stoke U21 v Southampton U21 | W | 0-3 |
| England Premier League 2 | 2022/08/12 17:00 | Southampton U21 v West Brom U21 | W | 4-1 |
| England Premier League 2 | 2022/08/08 18:00 | Nottm Forest U21 v Southampton U21 | W | 1-3 |
| England EFL Trophy | 2021/11/09 19:00 | Crawley Town v Southampton U21 | W | 0-4 |
| England EFL Trophy | 2021/10/05 18:00 | Charlton v Southampton U21 | L | 4-1 |