[2] BUF Sabres 3-5 TB Lightning [3] 2022-11-05 23:00
Stadium: Amalie Arena
Home Manager: Jon Cooper Away Manager: Don Granato
Head to Head
| NHL | 2022/04/10 21:00 | BUF Sabres v TB Lightning | L | 0-5 |
| NHL | 2022/01/12 00:00 | TB Lightning v BUF Sabres | L | 6-1 |
| NHL | 2021/10/25 23:00 | TB Lightning v BUF Sabres | W | 1-5 |
| NHL | 2020/01/01 00:00 | TB Lightning v BUF Sabres | L | 6-4 |
| NHL | 2019/11/26 00:00 | BUF Sabres v TB Lightning | L | 2-5 |
| NHL | 2019/11/09 18:00 | BUF Sabres v TB Lightning | L | 3-5 |
| NHL | 2019/11/08 19:00 | TB Lightning v BUF Sabres | L | 3-2 |
| NHL | 2019/02/22 00:30 | BUF Sabres v TB Lightning | L | 1-2 |
Home History
| NHL | 2022/11/04 23:00 | BUF Sabres v CAR Hurricanes | L | 3-5 |
| NHL | 2022/11/02 23:30 | PIT Penguins v BUF Sabres | W | 3-6 |
| NHL | 2022/10/31 23:00 | DET Red Wings v BUF Sabres | W | 3-8 |
| NHL | 2022/10/29 23:00 | CHI Blackhawks v BUF Sabres | W | 3-4 |
| NHL | 2022/10/27 23:00 | MON Canadiens v BUF Sabres | L | 3-2 |
| NHL | 2022/10/26 02:00 | BUF Sabres v SEA Kraken | L | 1-5 |
| NHL | 2022/10/23 02:00 | BUF Sabres v VAN Canucks | W | 5-1 |
| NHL | 2022/10/21 01:30 | BUF Sabres v CAL Flames | W | 6-3 |
Away History
| NHL | 2022/11/03 23:00 | CAR Hurricanes v TB Lightning | L | 4-3 |
| NHL | 2022/11/01 23:00 | OTT Senators v TB Lightning | W | 3-4 |
| NHL | 2022/10/29 20:30 | TB Lightning v SJ Sharks | W | 4-3 |
| NHL | 2022/10/27 02:00 | TB Lightning v ANA Ducks | W | 4-2 |
| NHL | 2022/10/26 02:30 | TB Lightning v LA Kings | L | 2-4 |
| NHL | 2022/10/22 23:00 | NY Islanders v TB Lightning | W | 3-5 |
| NHL | 2022/10/21 23:30 | TB Lightning v FLA Panthers | W | 3-2 |
| NHL | 2022/10/18 23:00 | PHI Flyers v TB Lightning | L | 3-2 |