[2] BOS Bruins 3-1 BUF Sabres [21] 2022-11-13 00:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Jim Montgomery
Head to Head
| NHL | 2022/04/28 23:00 | BUF Sabres v BOS Bruins | W | 0-5 |
| NHL | 2022/01/01 18:00 | BUF Sabres v BOS Bruins | W | 3-4 |
| NHL | 2021/11/25 00:00 | BOS Bruins v BUF Sabres | W | 5-1 |
| NHL | 2021/10/22 23:00 | BOS Bruins v BUF Sabres | W | 4-1 |
| NHL | 2021/05/01 17:00 | BUF Sabres v BOS Bruins | W | 2-6 |
| NHL | 2021/04/29 23:00 | BUF Sabres v BOS Bruins | W | 2-5 |
| NHL | 2021/04/23 23:00 | BOS Bruins v BUF Sabres | L | 4-6 |
| NHL | 2021/04/22 23:00 | BOS Bruins v BUF Sabres | W | 5-1 |
Home History
| NHL | 2022/11/11 00:00 | CAL Flames v BOS Bruins | W | 1-3 |
| NHL | 2022/11/08 00:00 | STL Blues v BOS Bruins | W | 1-3 |
| NHL | 2022/11/05 23:00 | BOS Bruins v TOR Maple Leafs | L | 1-2 |
| NHL | 2022/11/03 23:30 | BOS Bruins v NY Rangers | W | 5-2 |
| NHL | 2022/11/02 00:00 | BOS Bruins v PIT Penguins | W | 6-5 |
| NHL | 2022/10/28 23:00 | BOS Bruins v CLB Blue Jackets | W | 4-0 |
| NHL | 2022/10/27 23:00 | DET Red Wings v BOS Bruins | W | 1-5 |
| NHL | 2022/10/25 23:00 | DAL Stars v BOS Bruins | W | 1-3 |
Away History
| NHL | 2022/11/11 00:00 | VGS Golden Knights v BUF Sabres | L | 7-4 |
| NHL | 2022/11/09 00:00 | ARZ Coyotes v BUF Sabres | L | 4-1 |
| NHL | 2022/11/05 23:00 | BUF Sabres v TB Lightning | L | 3-5 |
| NHL | 2022/11/04 23:00 | BUF Sabres v CAR Hurricanes | L | 3-5 |
| NHL | 2022/11/02 23:30 | PIT Penguins v BUF Sabres | W | 3-6 |
| NHL | 2022/10/31 23:00 | DET Red Wings v BUF Sabres | W | 3-8 |
| NHL | 2022/10/29 23:00 | CHI Blackhawks v BUF Sabres | W | 3-4 |
| NHL | 2022/10/27 23:00 | MON Canadiens v BUF Sabres | L | 3-2 |