Syracuse 10-56 Louisville 2017-11-18 20:30
Stadium: L&N Federal Credit Union Stadium Round: 1
Home Manager: Bobby Petrino Away Manager: Dino Babers
Head to Head
| NCAAF | 2016/09/10 00:00 | Louisville v Syracuse | L | 62-28 |
| NCAAF | 2015/11/07 17:30 | Louisville v Syracuse | L | 41-17 |
| NCAAF | 2014/10/03 23:00 | Syracuse v Louisville | L | 6-28 |
| NCAAF | 2012/11/10 12:00 | Syracuse v Louisville | W | 45-26 |
| NCAAF | 2011/10/29 12:00 | Louisville v Syracuse | L | 27-10 |
| NCAAF | 2010/11/06 12:00 | Syracuse v Louisville | L | 20-28 |
| NCAAF | 2009/11/14 12:00 | Louisville v Syracuse | L | 10-9 |
| NCAAF | 2008/11/01 12:00 | Syracuse v Louisville | W | 28-21 |
Home History
| NCAAF | 2017/11/11 20:00 | Wake Forest v Syracuse | L | 64-43 |
| NCAAF | 2017/11/04 16:20 | Syracuse v Florida State | L | 24-27 |
| NCAAF | 2017/10/21 21:30 | Miami Florida v Syracuse | L | 27-19 |
| NCAAF | 2017/10/21 19:30 | Syracuse v Miami Florida | L | 19-27 |
| NCAAF | 2017/10/13 23:00 | Clemson v Syracuse | W | 24-27 |
| NCAAF | 2017/10/07 16:30 | Pittsburgh v Syracuse | W | 24-27 |
| NCAAF | 2017/09/30 16:20 | Syracuse v NC State | L | 25-33 |
| NCAAF | 2017/09/23 23:00 | Syracuse v LSU | L | 26-35 |
Away History
| NCAAF | 2017/11/11 20:30 | Virginia v Louisville | W | 21-38 |
| NCAAF | 2017/10/28 16:20 | Louisville v Wake Forest | L | 32-42 |
| NCAAF | 2017/10/21 16:00 | Florida State v Louisville | W | 28-31 |
| NCAAF | 2017/10/21 16:00 | Louisville v Florida State | W | 31-28 |
| NCAAF | 2017/10/14 16:20 | Boston College v Louisville | L | 45-42 |
| NCAAF | 2017/10/06 00:00 | Louisville v NC State | L | 25-39 |
| NCAAF | 2017/09/30 19:30 | Murray State v Louisville | W | 10-55 |
| NCAAF | 2017/09/23 18:00 | Kent State v Louisville | W | 3-42 |