PHI Flyers 1-2 BUF Sabres 2022-09-27 23:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: John Tortorella
Head to Head
| NHL | 2022/04/17 21:00 | BUF Sabres v PHI Flyers | L | 5-3 |
| NHL | 2022/04/16 23:00 | PHI Flyers v BUF Sabres | L | 3-4 |
| NHL | 2022/01/22 18:00 | PHI Flyers v BUF Sabres | L | 3-6 |
| NHL | 2021/04/11 18:00 | BUF Sabres v PHI Flyers | L | 5-3 |
| NHL | 2021/03/31 23:30 | PHI Flyers v BUF Sabres | L | 1-6 |
| NHL | 2021/03/29 23:00 | PHI Flyers v BUF Sabres | W | 4-3 |
| NHL | 2021/03/10 00:00 | BUF Sabres v PHI Flyers | W | 4-5 |
| NHL | 2021/02/28 20:00 | PHI Flyers v BUF Sabres | W | 3-0 |
Home History
| NHL Pre-Season | 2022/09/24 23:00 | BOS Bruins v PHI Flyers | W | 1-2 |
| NHL | 2022/04/29 23:00 | OTT Senators v PHI Flyers | L | 4-2 |
| NHL | 2022/04/27 23:30 | PHI Flyers v WIN Jets | L | 0-4 |
| NHL | 2022/04/26 00:00 | PHI Flyers v CHI Blackhawks | L | 1-3 |
| NHL | 2022/04/24 20:00 | PIT Penguins v PHI Flyers | W | 1-4 |
| NHL | 2022/04/21 23:00 | PHI Flyers v MON Canadiens | W | 6-3 |
| NHL | 2022/04/19 23:00 | PHI Flyers v TOR Maple Leafs | L | 2-5 |
| NHL | 2022/04/17 21:00 | BUF Sabres v PHI Flyers | L | 5-3 |
Away History
| NHL Pre-Season | 2022/09/25 18:00 | BUF Sabres v WAS Capitals | W | 4-3 |
| NHL | 2022/04/29 23:00 | CHI Blackhawks v BUF Sabres | W | 2-3 |
| NHL | 2022/04/28 23:00 | BUF Sabres v BOS Bruins | L | 0-5 |
| NHL | 2022/04/23 16:30 | NY Islanders v BUF Sabres | W | 3-5 |
| NHL | 2022/04/21 23:00 | BUF Sabres v NJ Devils | W | 5-2 |
| NHL | 2022/04/17 21:00 | BUF Sabres v PHI Flyers | W | 5-3 |
| NHL | 2022/04/16 23:00 | PHI Flyers v BUF Sabres | W | 3-4 |
| NHL | 2022/04/14 23:00 | STL Blues v BUF Sabres | L | 6-2 |