[6] Real Santa Cruz 2-1 Oriente Petrolero [11] 2022-07-23 19:00
Stadium: Estadio Juan Carlos Duran Round: 5
Head to Head
| Bolivia Apertura | 2022/05/14 20:00 | Oriente Petrolero v Real Santa Cruz | W | 1-2 |
| Bolivia Apertura | 2022/04/02 19:00 | Real Santa Cruz v Oriente Petrolero | W | 2-1 |
| Bolivia Apertura | 2021/12/05 00:30 | Oriente Petrolero v Real Santa Cruz | L | 2-0 |
| Bolivia Apertura | 2021/08/07 19:00 | Real Santa Cruz v Oriente Petrolero | D | 0-0 |
| Bolivia Apertura | 2020/12/16 23:30 | Oriente Petrolero v Real Santa Cruz | L | 3-2 |
| Bolivia Apertura | 2020/02/16 19:00 | Real Santa Cruz v Oriente Petrolero | L | 1-5 |
Home History
| Bolivia Clausura | 2022/07/15 23:30 | Real Tomayapo v Real Santa Cruz | W | 1-2 |
| Bolivia Clausura | 2022/07/09 19:00 | Real Santa Cruz v Atletico Palmaflor Vinto | D | 0-0 |
| Bolivia Clausura | 2022/07/07 00:30 | Blooming v Real Santa Cruz | L | 5-1 |
| Bolivia Clausura | 2022/07/01 19:00 | Real Santa Cruz v Universitario de Sucre | W | 3-0 |
| Bolivia Apertura | 2022/05/21 19:00 | Real Santa Cruz v Atletico Palmaflor Vinto | L | 1-2 |
| Bolivia Apertura | 2022/05/14 20:00 | Oriente Petrolero v Real Santa Cruz | W | 1-2 |
| Bolivia Apertura | 2022/05/12 19:00 | Club Aurora v Real Santa Cruz | W | 2-4 |
| Bolivia Apertura | 2022/05/08 19:00 | Always Ready v Real Santa Cruz | L | 5-0 |
Away History
| Bolivia Clausura | 2022/07/17 23:30 | Blooming v Oriente Petrolero | D | 2-2 |
| Bolivia Clausura | 2022/07/09 00:00 | Oriente Petrolero v Royal Pari FC | L | 0-1 |
| Bolivia Clausura | 2022/07/06 00:30 | Universitario de Sucre v Oriente Petrolero | L | 2-0 |
| Bolivia Clausura | 2022/07/02 23:30 | Oriente Petrolero v The Strongest | W | 3-0 |
| Bolivia Apertura | 2022/06/03 00:00 | Bolivar v Oriente Petrolero | L | 8-6 |
| Bolivia Apertura | 2022/05/29 23:30 | Oriente Petrolero v Bolivar | W | 1-0 |
| Copa Sudamericana | 2022/05/27 00:30 | Oriente Petrolero v Fluminense | L | 1-10 |
| Bolivia Apertura | 2022/05/21 18:55 | Nacional Potosi v Oriente Petrolero | L | 4-2 |