| Colombia Regional League | 2021/06/26 19:13 | Real Santuario v Club Deportivo La Chalaca | D | 2-2 |
| Colombia Regional League | 2022/07/02 19:15 | Club Deportivo La Chalaca v Deportivo Alexis Garcia | L | 0-4 |
| Colombia Regional League | 2022/05/27 15:00 | Club Deportivo La Chalaca v Medellin City FC | W | 4-1 |
| Colombia Regional League | 2022/05/16 15:10 | Club Deportivo La Chalaca v Molino Viejo | W | 4-1 |
| Colombia Regional League | 2022/04/25 14:16 | Lula FC v Club Deportivo La Chalaca | L | 6-1 |
| Colombia Regional League | 2022/04/11 15:13 | Club Deportivo La Chalaca v Aguilas Doradas Reserves | D | 1-1 |
| Colombia Regional League | 2022/04/04 15:10 | Club Deportivo La Chalaca v Estudiantes de Medellin | W | 3-1 |
| Colombia Regional League | 2022/03/23 17:14 | Club Deportivo La Chalaca v Sellos Colombianos | W | 2-1 |
| Colombia Regional League | 2021/12/18 23:59 | Aguilas Doradas Reserves v Club Deportivo La Chalaca | L | 4-0 |
| Colombia Regional League | 2022/07/09 17:20 | Real Santuario v Real San Jeronimo | W | 3-2 |
| Colombia Regional League | 2022/06/11 17:18 | Real Santuario v Total Soccer FC | W | 3-0 |
| Colombia Regional League | 2022/06/05 21:17 | Ferrovalvulas FC v Real Santuario | L | 2-0 |
| Colombia Regional League | 2022/05/30 17:23 | Sol de Oriente v Real Santuario | L | 2-1 |
| Colombia Regional League | 2022/05/24 17:12 | Real Santuario v Politecnico J.I.C. | W | 3-0 |
| Colombia Regional League | 2022/05/10 13:15 | Real Santuario v Envigado FC Reserves | L | 1-3 |
| Colombia Regional League | 2022/04/23 17:18 | Real Santuario v FC Leones Reserves | D | 2-2 |
| Colombia Regional League | 2022/04/11 16:00 | Estudiantes de Medellin v Real Santuario | D | 1-1 |