[2] Sale Sharks 37-14 London Irish [10] 2022-10-14 18:45
Stadium: The AJ Bell Stadium Round: 6
Referee: Karl Dickson
Head to Head
| Premiership Rugby | 2022/02/25 19:45 | Sale Sharks v London Irish | D | 27-27 |
| Premiership Rugby | 2021/09/26 14:00 | London Irish v Sale Sharks | D | 31-31 |
| Premiership Rugby | 2021/03/21 15:00 | Sale Sharks v London Irish | W | 41-13 |
| Premiership Rugby | 2020/12/06 14:30 | London Irish v Sale Sharks | W | 13-21 |
| Premiership Rugby | 2020/03/06 20:00 | Sale Sharks v London Irish | W | 39-0 |
| Premiership Rugby | 2019/10/26 14:00 | London Irish v Sale Sharks | W | 7-41 |
| Premiership Rugby Cup | 2019/10/12 14:00 | London Irish v Sale Sharks | W | 22-27 |
| Premiership Rugby | 2018/02/10 15:00 | London Irish v Sale Sharks | W | 9-13 |
Home History
| Premiership Rugby | 2022/10/08 14:00 | Leicester v Sale Sharks | W | 16-26 |
| Premiership Rugby | 2022/10/01 14:00 | Sale Sharks v Exeter Chiefs | W | 28-20 |
| Premiership Rugby Cup | 2022/09/27 18:45 | Newcastle Falcons v Sale Sharks | W | 21-29 |
| Premiership Rugby Cup | 2022/09/20 18:45 | Sale Sharks v Leicester | W | 25-19 |
| Premiership Rugby | 2022/09/17 14:00 | Bath v Sale Sharks | W | 20-37 |
| Premiership Rugby | 2022/09/11 14:00 | Sale Sharks v Northampton | W | 29-22 |
| Premiership Rugby | 2022/06/04 14:00 | Sale Sharks v Bristol | W | 42-19 |
| Premiership Rugby | 2022/05/20 18:45 | Wasps v Sale Sharks | W | 7-16 |
Away History
| Premiership Rugby | 2022/10/01 14:00 | London Irish v Bath | W | 47-38 |
| Premiership Rugby Cup | 2022/09/27 18:45 | London Irish v Northampton | W | 28-26 |
| Premiership Rugby | 2022/09/24 14:00 | Bristol v London Irish | L | 40-36 |
| Premiership Rugby Cup | 2022/09/21 18:45 | Harlequins v London Irish | W | 26-30 |
| Premiership Rugby | 2022/09/17 13:00 | Northampton v London Irish | L | 38-22 |
| Premiership Rugby | 2022/05/21 14:00 | Bath v London Irish | L | 27-24 |
| Premiership Rugby Cup | 2022/05/17 18:45 | London Irish v Worcester Warriors | D | 25-25 |
| European Rugby Challenge Cup | 2022/05/08 11:30 | Toulon v London Irish | L | 19-18 |