Home History
| England EFL Trophy | 2022/10/04 18:30 | Barrow v Man Utd U21 | W | 1-2 |
| England Premier League 2 | 2022/10/01 11:00 | Blackburn U21 v Man Utd U21 | L | 6-1 |
| England Premier League 2 | 2022/09/16 18:00 | Man Utd U21 v West Ham U21 | D | 1-1 |
| England Premier League 2 | 2022/09/03 13:00 | Liverpool U21 v Man Utd U21 | D | 2-2 |
| England EFL Trophy | 2022/08/30 18:30 | Carlisle v Man Utd U21 | W | 1-2 |
| England Premier League 2 | 2022/08/26 18:00 | Man Utd U21 v Fulham U21 | D | 2-2 |
| England Premier League 2 | 2022/08/19 18:00 | Everton U21 v Man Utd U21 | D | 2-2 |
| England Premier League 2 | 2022/08/12 18:00 | Man Utd U21 v Crystal Palace U21 | L | 1-5 |
Away History
| England EFL Trophy | 2022/10/04 18:00 | Gillingham v Brighton U21 | L | 3-2 |
| England Premier League 2 | 2022/09/30 18:00 | Brighton U21 v Tottenham U21 | W | 4-0 |
| England Premier League 2 | 2022/09/18 11:00 | Everton U21 v Brighton U21 | L | 1-0 |
| England EFL Trophy | 2022/09/06 18:45 | Colchester v Brighton U21 | L | 2-1 |
| England Premier League 2 | 2022/09/03 12:00 | Leicester U21 v Brighton U21 | W | 1-4 |
| England Premier League 2 | 2022/08/26 18:00 | Brighton U21 v Arsenal U21 | D | 2-2 |
| England Premier League 2 | 2022/08/22 18:00 | Wolverhampton U21 v Brighton U21 | L | 2-0 |
| England Premier League 2 | 2022/08/14 14:00 | Brighton U21 v Liverpool U21 | D | 1-1 |