[4] CLB Blue Jackets 3-2 BUF Sabres [16] 2017-11-21 00:00
Stadium: KeyBank Center Round: 1
Home Manager: Phil Housley Away Manager: John Tortorella
Head to Head
| NHL | 2017/10/26 00:00 | BUF Sabres v CLB Blue Jackets | W | 1-5 |
| NHL | 2017/03/28 23:00 | BUF Sabres v CLB Blue Jackets | W | 1-3 |
| NHL | 2017/03/12 00:00 | CLB Blue Jackets v BUF Sabres | L | 3-5 |
| NHL | 2017/03/11 00:00 | BUF Sabres v CLB Blue Jackets | W | 3-4 |
Home History
| NHL | 2017/11/18 00:00 | NY Rangers v CLB Blue Jackets | W | 0-2 |
| NHL | 2017/11/15 00:30 | CLB Blue Jackets v MON Canadiens | W | 2-1 |
| NHL | 2017/11/12 00:00 | CLB Blue Jackets v DET Red Wings | W | 2-1 |
| NHL | 2017/11/11 00:00 | CAR Hurricanes v CLB Blue Jackets | L | 3-1 |
| NHL | 2017/11/08 00:00 | NAS Predators v CLB Blue Jackets | L | 3-1 |
| NHL | 2017/11/07 00:00 | CLB Blue Jackets v NY Rangers | L | 3-5 |
| NHL | 2017/11/04 23:00 | CLB Blue Jackets v TB Lightning | L | 4-5 |
| NHL | 2017/11/02 23:30 | CLB Blue Jackets v FLA Panthers | W | 7-3 |
Away History
| NHL | 2017/11/19 00:00 | CAR Hurricanes v BUF Sabres | L | 3-1 |
| NHL | 2017/11/18 00:30 | BUF Sabres v DET Red Wings | L | 1-3 |
| NHL | 2017/11/15 00:00 | BUF Sabres v PIT Penguins | L | 4-5 |
| NHL | 2017/11/12 00:00 | BUF Sabres v MON Canadiens | L | 1-2 |
| NHL | 2017/11/11 00:00 | FLA Panthers v BUF Sabres | L | 4-1 |
| NHL | 2017/11/08 00:00 | WAS Capitals v BUF Sabres | W | 1-3 |
| NHL | 2017/11/05 00:00 | BUF Sabres v DAL Stars | L | 1-5 |
| NHL | 2017/11/03 02:00 | BUF Sabres v ARZ Coyotes | W | 5-4 |