Stadium: Memorial Stadium (Terre Haute) Round: 1
Home Manager: Curt Mallory Away Manager: Bubba Schweigert
| NCAAF | 2022/10/29 20:00 | Abilene Christian v North Dakota | W | 31-34 |
| NCAAF | 2022/10/22 20:00 | South Dakota State v North Dakota | L | 49-35 |
| NCAAF | 2022/10/08 22:00 | North Dakota v Youngstown State | W | 35-30 |
| NCAAF | 2022/10/01 17:00 | Missouri St v North Dakota | W | 31-48 |
| NCAAF | 2022/09/24 19:00 | North Dakota v SO Illinois | L | 17-34 |
| NCAAF | 2022/09/17 20:00 | North Dakota v Northern Arizona | W | 27-24 |
| NCAAF | 2022/09/10 20:00 | Northern Iowa v North Dakota | W | 27-29 |
| NCAAF | 2022/09/03 19:30 | North Dakota v Nebraska | L | 17-38 |
| NCAAF | 2022/10/29 19:00 | Indiana State v South Dakota State | L | 7-49 |
| NCAAF | 2022/10/22 17:00 | Illinois State v Indiana State | L | 27-21 |
| NCAAF | 2022/10/15 18:00 | Indiana State v Youngstown State | L | 42-48 |
| NCAAF | 2022/10/08 17:00 | North Dakota State v Indiana State | L | 31-26 |
| NCAAF | 2022/10/01 21:00 | Indiana State v Northern Iowa | L | 14-20 |
| NCAAF | 2022/09/17 17:00 | Montana v Indiana State | L | 49-14 |
| NCAAF | 2022/09/10 20:00 | Indiana State v Purdue | L | 0-56 |
| NCAAF | 2022/09/01 22:00 | North Alabama v Indiana State | W | 14-17 |