Stadium: William B. Greene Jr. Stadium Round: 1
Home Manager: George Quarles Away Manager:
| NCAAF | 2021/11/13 19:00 | East Tennessee State v Western Carolina | L | 56-35 |
| NCAAF | 2021/03/27 17:00 | Western Carolina v East Tennessee State | L | 17-24 |
| NCAAF | 2019/11/09 20:30 | East Tennessee State v Western Carolina | W | 20-23 |
| NCAAF | 2018/10/27 19:30 | East Tennessee State v Western Carolina | L | 45-43 |
| NCAAF | 2017/10/14 19:30 | Western Carolina v East Tennessee State | W | 49-10 |
| NCAAF | 2022/11/05 18:00 | Wofford v Western Carolina | W | 29-36 |
| NCAAF | 2022/10/22 18:00 | The Citadel v Western Carolina | L | 34-21 |
| NCAAF | 2022/10/15 18:00 | Western Carolina v Furman | L | 40-47 |
| NCAAF | 2022/10/08 20:00 | Western Carolina v Mercer | L | 6-49 |
| NCAAF | 2022/10/01 19:30 | VMI v Western Carolina | W | 17-38 |
| NCAAF | 2022/09/24 19:00 | Western Carolina v Samford | L | 12-35 |
| NCAAF | 2022/09/17 19:30 | Presbyterian v Western Carolina | W | 21-77 |
| NCAAF | 2022/09/10 23:00 | Western Carolina v Georgia Tech | L | 17-35 |
| NCAAF | 2022/10/29 17:30 | East Tennessee State v Wofford | L | 41-48 |
| NCAAF | 2022/10/22 19:30 | Samford v East Tennessee State | L | 55-45 |
| NCAAF | 2022/10/15 20:00 | East Tennessee State v Mercer | L | 33-55 |
| NCAAF | 2022/10/08 17:30 | East Tennessee State v VMI | W | 44-21 |
| NCAAF | 2022/10/01 19:00 | Tennessee Chattanooga v East Tennessee State | L | 24-16 |
| NCAAF | 2022/09/24 16:00 | East Tennessee State v Robert Morris | W | 45-3 |
| NCAAF | 2022/09/17 23:30 | Furman v East Tennessee State | L | 27-14 |
| NCAAF | 2022/09/10 20:00 | East Tennessee State v The Citadel | L | 17-20 |