Stadium: Paladin Stadium Round: 1
Home Manager: Clay Hendrix Away Manager:
| NCAAF | 2021/11/20 18:00 | Furman v Samford | W | 41-34 |
| NCAAF | 2021/11/13 19:00 | VMI v Furman | W | 31-37 |
| NCAAF | 2021/11/06 18:00 | Furman v Western Carolina | L | 42-43 |
| NCAAF | 2021/10/30 17:30 | Furman v Tennessee Chattanooga | L | 3-13 |
| NCAAF | 2021/10/23 18:00 | East Tennessee State v Furman | L | 17-13 |
| NCAAF | 2021/10/16 22:00 | The Citadel v Furman | W | 14-24 |
| NCAAF | 2021/10/09 17:30 | Furman v Wofford | W | 42-20 |
| NCAAF | 2021/09/25 18:00 | Mercer v Furman | L | 24-3 |
| NCAAF | 2021/11/13 17:00 | North Greenville Crusaders v Shorter | W | 56-0 |
| NCAAF | 2021/11/06 19:00 | Valdosta State v North Greenville Crusaders | L | 31-21 |
| NCAAF | 2021/10/30 16:00 | North Greenville Crusaders v West Alabama Tigers | L | 14-31 |
| NCAAF | 2021/10/23 22:00 | West Georgia v North Greenville Crusaders | L | 34-12 |
| NCAAF | 2021/10/16 19:00 | Delta State v North Greenville Crusaders | W | 34-42 |
| NCAAF | 2021/10/09 23:00 | North Greenville Crusaders v West Florida | L | 10-52 |
| NCAAF | 2021/10/02 19:00 | North Greenville Crusaders v Mississippi College Choctaws | L | 21-42 |
| NCAAF | 2021/09/25 17:00 | Erskine Flying Fleet v North Greenville Crusaders | W | 7-38 |