Head to Head
| England Premier League 2 | 2022/08/19 18:00 | Stoke U21 v Southampton U21 | W | 0-3 |
Home History
| England Premier League 2 | 2023/03/31 18:00 | Derby U21 v Southampton U21 | W | 1-3 |
| England Premier League 2 | 2023/03/17 18:00 | Aston Villa U21 v Southampton U21 | W | 1-2 |
| England U21 Premier League Cup | 2023/03/10 19:00 | Southampton U21 v Blackburn U21 | L | 1-4 |
| England Premier League 2 | 2023/03/03 19:00 | Southampton U21 v Nottm Forest U21 | L | 0-2 |
| England Premier League 2 | 2023/02/24 19:00 | Southampton U21 v Leeds U21 | L | 1-2 |
| England Premier League 2 | 2023/02/20 19:00 | West Brom U21 v Southampton U21 | W | 1-2 |
| England Premier League 2 | 2023/02/10 12:00 | Southampton U21 v Sunderland U21 | D | 2-2 |
| England U21 Premier League Cup | 2023/02/03 13:00 | Southampton U21 v Sheff Utd U21 | W | 1-0 |
Away History
| England Premier League 2 | 2023/03/20 19:00 | Derby U21 v Stoke U21 | W | 1-6 |
| England U21 Premier League Cup | 2023/03/11 13:00 | Stoke U21 v Fulham U21 | L | 1-6 |
| England Premier League 2 | 2023/03/06 19:00 | Sunderland U21 v Stoke U21 | L | 4-1 |
| England Premier League 2 | 2023/02/24 19:00 | Stoke U21 v Newcastle U21 | D | 2-2 |
| England Premier League 2 | 2023/02/20 18:00 | Stoke U21 v Middlesbrough U21 | L | 1-2 |
| England Premier League 2 | 2023/02/10 19:00 | Aston Villa U21 v Stoke U21 | L | 1-0 |
| England U21 Premier League Cup | 2023/02/06 19:00 | Wolverhampton U21 v Stoke U21 | W | 2-3 |
| Premier League International Cup | 2023/02/01 19:00 | Stoke U21 v Dinamo Zagreb U21 | L | 1-3 |