Head to Head
| England Premier League 2 | 2022/10/30 12:00 | Southampton U21 v Middlesbrough U21 | L | 8-1 |
Home History
| England Premier League 2 | 2023/01/09 19:00 | Sunderland U21 v Middlesbrough U21 | W | 5-7 |
| England U21 Premier League Cup | 2023/01/05 14:00 | West Brom U21 v Middlesbrough U21 | W | 0-1 |
| England U21 Premier League Cup | 2022/12/20 13:30 | Watford U21 v Middlesbrough U21 | L | 3-1 |
| England U21 Premier League Cup | 2022/11/25 13:00 | Huddersfield U21 v Middlesbrough U21 | L | 2-0 |
| England U21 Premier League Cup | 2022/11/19 11:00 | Middlesbrough U21 v Watford U21 | W | 4-0 |
| England Premier League 2 | 2022/10/30 12:00 | Southampton U21 v Middlesbrough U21 | L | 8-1 |
| England Premier League 2 | 2022/10/22 10:00 | Middlesbrough U21 v Leeds U21 | L | 2-4 |
| England U21 Premier League Cup | 2022/10/17 17:00 | Middlesbrough U21 v West Brom U21 | W | 2-1 |
Away History
| England Premier League 2 | 2023/01/13 19:00 | Southampton U21 v Newcastle U21 | W | 4-1 |
| England Premier League 2 | 2023/01/06 19:00 | Southampton U21 v Derby U21 | W | 3-0 |
| England U21 Premier League Cup | 2022/12/16 12:00 | Birmingham U21 v Southampton U21 | D | 2-2 |
| England U21 Premier League Cup | 2022/12/02 19:00 | Southampton U21 v Colchester U21 | W | 7-1 |
| England U21 Premier League Cup | 2022/11/26 13:00 | Colchester U21 v Southampton U21 | W | 0-5 |
| England U21 Premier League Cup | 2022/11/21 19:00 | Southampton U21 v Birmingham U21 | W | 4-0 |
| England U21 Premier League Cup | 2022/11/13 12:00 | Everton U21 v Southampton U21 | W | 1-2 |
| England Premier League 2 | 2022/11/07 13:00 | Sunderland U21 v Southampton U21 | W | 1-3 |