Home History
| England Premier League 2 | 2022/08/29 12:00 | Leeds U21 v Nottm Forest U21 | W | 5-1 |
| England Premier League 2 | 2022/08/19 18:00 | Aston Villa U21 v Leeds U21 | W | 1-2 |
| England Premier League 2 | 2022/08/15 11:00 | Leeds U21 v Norwich U21 | D | 2-2 |
| England Premier League 2 | 2022/08/05 17:00 | Derby U21 v Leeds U21 | W | 2-5 |
| England EFL Trophy | 2021/11/02 19:15 | Salford City v Leeds U21 | L | 5-3 |
| England EFL Trophy | 2021/09/28 18:00 | Oldham v Leeds U21 | W | 2-3 |
| England EFL Trophy | 2021/09/14 18:00 | Tranmere v Leeds U21 | L | 4-1 |
| England EFL Trophy | 2020/11/11 19:00 | Blackpool v Leeds U21 | L | 3-0 |
Away History
| England EFL Trophy | 2022/08/30 18:00 | Forest Green v Southampton U21 | L | 3-1 |
| England Premier League 2 | 2022/08/26 18:00 | Southampton U21 v Norwich U21 | D | 1-1 |
| England Premier League 2 | 2022/08/19 18:00 | Stoke U21 v Southampton U21 | W | 0-3 |
| England Premier League 2 | 2022/08/12 17:00 | Southampton U21 v West Brom U21 | W | 4-1 |
| England Premier League 2 | 2022/08/08 18:00 | Nottm Forest U21 v Southampton U21 | W | 1-3 |
| England EFL Trophy | 2021/11/09 19:00 | Crawley Town v Southampton U21 | W | 0-4 |
| England EFL Trophy | 2021/10/05 18:00 | Charlton v Southampton U21 | L | 4-1 |
| England EFL Trophy | 2021/09/14 18:00 | Leyton Orient v Southampton U21 | L | 1-0 |