[10] Indiana 14-56 Ohio State [1] 2022-11-12 17:00
Stadium: Ohio Stadium Round: 1
Home Manager: Ryan Day Away Manager: Tom Allen
Head to Head
| NCAAF | 2021/10/23 23:30 | Ohio State v Indiana | L | 54-7 |
| NCAAF | 2020/11/21 17:00 | Indiana v Ohio State | L | 35-42 |
| NCAAF | 2019/09/14 16:00 | Ohio State v Indiana | L | 51-10 |
| NCAAF | 2018/10/06 20:00 | Indiana v Ohio State | L | 26-49 |
| NCAAF | 2017/09/01 00:00 | Ohio State v Indiana | L | 49-21 |
| NCAAF | 2016/10/08 19:30 | Indiana v Ohio State | L | 17-38 |
| NCAAF | 2015/10/03 19:30 | Indiana v Ohio State | L | 27-34 |
| NCAAF | 2014/11/22 17:00 | Ohio State v Indiana | L | 42-27 |
Home History
| NCAAF | 2022/11/05 19:30 | Penn State v Indiana | L | 45-14 |
| NCAAF | 2022/10/22 16:00 | Indiana v Rutgers | L | 17-24 |
| NCAAF | 2022/10/15 19:30 | Maryland v Indiana | L | 38-33 |
| NCAAF | 2022/10/08 16:00 | Michigan v Indiana | L | 31-10 |
| NCAAF | 2022/10/01 23:30 | Indiana v Nebraska | L | 21-35 |
| NCAAF | 2022/09/24 19:30 | Indiana v Cincinnati | L | 24-45 |
| NCAAF | 2022/09/17 16:00 | Western Kentucky v Indiana | W | 30-33 |
| NCAAF | 2022/09/11 00:00 | Idaho v Indiana | W | 22-35 |
Away History
| NCAAF | 2022/11/05 16:00 | Ohio State v Northwestern | W | 21-7 |
| NCAAF | 2022/10/29 16:00 | Ohio State v Penn State | W | 44-31 |
| NCAAF | 2022/10/22 16:00 | Iowa v Ohio State | W | 10-54 |
| NCAAF | 2022/10/08 20:00 | Ohio State v Michigan State | W | 49-20 |
| NCAAF | 2022/10/01 19:30 | Rutgers v Ohio State | W | 10-49 |
| NCAAF | 2022/09/24 23:30 | Wisconsin v Ohio State | W | 21-52 |
| NCAAF | 2022/09/17 23:00 | Toledo v Ohio State | W | 21-77 |
| NCAAF | 2022/09/10 16:00 | Arkansas State v Ohio State | W | 12-45 |