[3] Alabama 30-24 Mississippi [5] 2022-11-12 20:30
Stadium: Vaught-Hemingway Stadium Round: 1
Home Manager: Lane Kiffin Away Manager: Nick Saban
Head to Head
| NCAAF | 2021/10/02 19:30 | Mississippi v Alabama | W | 21-42 |
| NCAAF | 2020/10/10 23:30 | Alabama v Mississippi | W | 63-48 |
| NCAAF | 2019/09/28 19:30 | Mississippi v Alabama | W | 31-59 |
| NCAAF | 2018/09/15 23:00 | Alabama v Mississippi | W | 62-7 |
| NCAAF | 2017/10/01 01:00 | Mississippi v Alabama | W | 3-66 |
| NCAAF | 2016/09/17 19:30 | Alabama v Mississippi | W | 48-43 |
| NCAAF | 2015/09/20 01:15 | Alabama v Mississippi | L | 37-43 |
| NCAAF | 2014/10/04 19:30 | Mississippi v Alabama | L | 23-17 |
Home History
| NCAAF | 2022/11/05 23:00 | Alabama v LSU | L | 31-32 |
| NCAAF | 2022/11/03 23:30 | Alabama v Mississippi Valley State | L | 20-30 |
| NCAAF | 2022/10/29 19:30 | Alabama State v Alabama | L | 24-17 |
| NCAAF | 2022/10/22 23:00 | Mississippi State v Alabama | W | 6-30 |
| NCAAF | 2022/10/16 20:00 | Alabama v Arkansas Pine Bluff | W | 34-31 |
| NCAAF | 2022/10/15 19:30 | Alabama v Tennessee | L | 49-52 |
| NCAAF | 2022/10/09 00:00 | Texas A&M v Alabama | W | 20-24 |
| NCAAF | 2022/10/08 18:00 | Grambling State v Alabama | W | 31-37 |
Away History
| NCAAF | 2022/10/29 23:30 | Mississippi v Texas A&M | W | 31-28 |
| NCAAF | 2022/10/22 19:30 | Mississippi v LSU | L | 20-45 |
| NCAAF | 2022/10/15 16:00 | Auburn v Mississippi | W | 34-48 |
| NCAAF | 2022/10/08 20:00 | Mississippi v Vanderbilt | W | 52-28 |
| NCAAF | 2022/10/01 16:00 | Kentucky v Mississippi | W | 19-22 |
| NCAAF | 2022/09/24 20:00 | Tulsa v Mississippi | W | 27-35 |
| NCAAF | 2022/09/17 19:30 | Mississippi v Georgia Tech | W | 42-0 |
| NCAAF | 2022/09/10 23:00 | Central Arkansas v Mississippi | W | 3-59 |