[6] Auburn 34-48 Mississippi [5] 2022-10-15 16:00
Stadium: Vaught-Hemingway Stadium Round: 1
Home Manager: Lane Kiffin Away Manager: Bryan Harsin
Head to Head
| NCAAF | 2021/10/30 23:00 | Mississippi v Auburn | W | 20-31 |
| NCAAF | 2020/10/24 16:00 | Auburn v Mississippi | W | 35-28 |
| NCAAF | 2019/11/02 23:00 | Mississippi v Auburn | W | 14-20 |
| NCAAF | 2018/10/20 16:00 | Auburn v Mississippi | W | 31-16 |
| NCAAF | 2017/10/07 16:00 | Mississippi v Auburn | W | 23-44 |
| NCAAF | 2016/10/29 23:15 | Auburn v Mississippi | W | 40-29 |
| NCAAF | 2015/10/31 16:00 | Auburn v Mississippi | L | 19-27 |
| NCAAF | 2014/11/01 23:00 | Mississippi v Auburn | W | 31-35 |
Home History
| NCAAF | 2022/10/08 19:30 | Auburn v Georgia | L | 10-42 |
| NCAAF | 2022/10/01 23:00 | LSU v Auburn | L | 21-17 |
| NCAAF | 2022/09/24 16:00 | Missouri v Auburn | W | 14-17 |
| NCAAF | 2022/09/17 19:30 | Penn State v Auburn | L | 41-12 |
| NCAAF | 2022/09/10 23:30 | San Jose State v Auburn | W | 16-24 |
| NCAAF | 2022/09/03 23:00 | Mercer v Auburn | W | 16-42 |
| NCAAF Bowl Games | 2021/12/28 17:00 | Houston v Auburn | L | 17-13 |
| NCAAF | 2021/11/27 20:30 | Alabama v Auburn | L | 24-22 |
Away History
| NCAAF | 2022/10/08 20:00 | Mississippi v Vanderbilt | W | 52-28 |
| NCAAF | 2022/10/01 16:00 | Kentucky v Mississippi | W | 19-22 |
| NCAAF | 2022/09/24 20:00 | Tulsa v Mississippi | W | 27-35 |
| NCAAF | 2022/09/17 19:30 | Mississippi v Georgia Tech | W | 42-0 |
| NCAAF | 2022/09/10 23:00 | Central Arkansas v Mississippi | W | 3-59 |
| NCAAF | 2022/09/03 20:00 | Troy v Mississippi | W | 10-28 |
| NCAAF Bowl Games | 2022/01/02 01:45 | Baylor v Mississippi | L | 21-7 |
| NCAAF | 2021/11/26 00:30 | Mississippi v Mississippi State | W | 31-21 |