[1] Clemson 31-3 Boston College [9] 2022-10-08 23:30
Stadium: Alumni Stadium Round: 1
Home Manager: Jeff Hafley Away Manager: Dabo Swinney
Head to Head
| NCAAF | 2021/10/02 23:30 | Boston College v Clemson | W | 13-19 |
| NCAAF | 2020/10/31 16:00 | Boston College v Clemson | W | 28-34 |
| NCAAF | 2019/10/26 23:30 | Clemson v Boston College | W | 59-7 |
| NCAAF | 2018/11/11 01:00 | Clemson v Boston College | W | 27-7 |
| NCAAF | 2017/09/23 19:30 | Clemson v Boston College | W | 34-7 |
| NCAAF | 2017/09/23 19:30 | Boston College v Clemson | W | 7-34 |
| NCAAF | 2016/10/07 23:30 | Clemson v Boston College | W | 56-10 |
| NCAAF | 2015/10/17 23:00 | Clemson v Boston College | W | 34-17 |
Home History
| NCAAF | 2022/10/01 23:30 | NC State v Clemson | W | 20-30 |
| NCAAF | 2022/09/24 16:00 | Clemson v Wake Forest | W | 51-45 |
| NCAAF | 2022/09/18 00:00 | Louisiana Tech v Clemson | W | 20-48 |
| NCAAF | 2022/09/10 19:30 | Furman v Clemson | W | 12-35 |
| NCAAF | 2022/09/06 00:00 | Clemson v Georgia Tech | W | 41-10 |
| NCAAF Bowl Games | 2021/12/29 22:45 | Iowa State v Clemson | W | 13-20 |
| NCAAF | 2021/11/28 00:30 | Clemson v South Carolina | W | 30-0 |
| NCAAF | 2021/11/20 17:00 | Wake Forest v Clemson | W | 27-48 |
Away History
| NCAAF | 2022/10/01 16:00 | Louisville v Boston College | W | 33-34 |
| NCAAF | 2022/09/25 00:00 | Boston College v Florida State | L | 14-44 |
| NCAAF | 2022/09/17 23:30 | Maine v Boston College | W | 17-38 |
| NCAAF | 2022/09/11 00:00 | Boston College v Virginia Tech | L | 10-27 |
| NCAAF | 2022/09/03 16:00 | Rutgers v Boston College | L | 22-21 |
| NCAAF | 2021/11/27 17:00 | Wake Forest v Boston College | L | 41-10 |
| NCAAF | 2021/11/20 17:00 | Florida State v Boston College | L | 26-23 |
| NCAAF | 2021/11/13 20:30 | Boston College v Georgia Tech | W | 41-30 |