[3] Toledo 27-24 Eastern Michigan [10] 2022-10-29 16:00
Stadium: Rynearson Stadium Round: 1
Home Manager: Chris Creighton Away Manager: Jason Candle
Head to Head
| NCAAF | 2021/11/02 23:30 | Eastern Michigan v Toledo | L | 52-49 |
| NCAAF | 2020/11/19 00:00 | Toledo v Eastern Michigan | W | 45-28 |
| NCAAF | 2019/10/26 19:30 | Eastern Michigan v Toledo | W | 34-37 |
| NCAAF | 2018/10/13 16:00 | Toledo v Eastern Michigan | L | 26-28 |
| NCAAF | 2017/10/07 16:00 | Eastern Michigan v Toledo | W | 15-20 |
| NCAAF | 2016/10/08 19:00 | Toledo v Eastern Michigan | W | 35-20 |
| NCAAF | 2015/10/17 16:00 | Toledo v Eastern Michigan | W | 63-20 |
| NCAAF | 2014/11/28 18:00 | Eastern Michigan v Toledo | W | 16-52 |
Home History
| NCAAF | 2022/10/22 17:00 | Toledo v Buffalo | L | 27-34 |
| NCAAF | 2022/10/15 19:30 | Kent State v Toledo | W | 31-52 |
| NCAAF | 2022/10/08 19:30 | Toledo v Northern Illinois | W | 52-32 |
| NCAAF | 2022/10/01 19:30 | Central Michigan v Toledo | W | 17-38 |
| NCAAF | 2022/09/24 19:30 | Toledo v San Diego State | L | 14-17 |
| NCAAF | 2022/09/17 23:00 | Toledo v Ohio State | L | 21-77 |
| NCAAF | 2022/09/10 23:00 | Massachusetts v Toledo | W | 10-55 |
| NCAAF | 2022/09/01 23:00 | LIU Brooklyn v Toledo | W | 0-37 |
Away History
| NCAAF | 2022/10/22 18:00 | Eastern Michigan v Ball State | W | 20-16 |
| NCAAF | 2022/10/15 19:30 | Northern Illinois v Eastern Michigan | L | 39-10 |
| NCAAF | 2022/10/08 16:00 | Eastern Michigan v Western Michigan | W | 45-23 |
| NCAAF | 2022/10/01 18:00 | Massachusetts v Eastern Michigan | W | 13-20 |
| NCAAF | 2022/09/24 16:00 | Buffalo v Eastern Michigan | L | 50-31 |
| NCAAF | 2022/09/18 03:00 | Eastern Michigan v Arizona State | W | 30-21 |
| NCAAF | 2022/09/10 23:00 | Eastern Michigan v Lafayette | L | 21-49 |
| NCAAF | 2022/09/02 23:00 | Eastern Kentucky v Eastern Michigan | W | 34-42 |