[8] Northern Illinois 17-24 Ohio [11] 2022-10-22 18:00
Stadium: Peden Stadium Round: 1
Home Manager: Tim Albin Away Manager: Thomas Hammock
Head to Head
| NCAAF | 2019/10/12 19:30 | Northern Illinois v Ohio | W | 39-36 |
| NCAAF | 2018/10/13 19:30 | Ohio v Northern Illinois | W | 21-24 |
| NCAAF | 2015/11/25 00:30 | Northern Illinois v Ohio | L | 21-26 |
| NCAAF | 2014/11/19 01:00 | Ohio v Northern Illinois | W | 14-21 |
| NCAAF | 2011/12/02 12:00 | Northern Illinois v Ohio | W | 23-20 |
| NCAAF | 2009/11/21 12:00 | Ohio v Northern Illinois | L | 38-31 |
| NCAAF | 2006/09/09 12:00 | Northern Illinois v Ohio | L | 23-35 |
| NCAAF | 2003/10/04 12:00 | Northern Illinois v Ohio | W | 30-23 |
Home History
| NCAAF | 2022/10/15 19:30 | Northern Illinois v Eastern Michigan | W | 39-10 |
| NCAAF | 2022/10/08 19:30 | Toledo v Northern Illinois | L | 52-32 |
| NCAAF | 2022/10/01 18:00 | Northern Illinois v Ball State | L | 38-44 |
| NCAAF | 2022/09/24 23:00 | Northern Illinois v Kentucky | L | 23-31 |
| NCAAF | 2022/09/17 19:30 | Vanderbilt v Northern Illinois | L | 38-28 |
| NCAAF | 2022/09/10 23:00 | Northern Illinois v Tulsa | L | 35-38 |
| NCAAF | 2022/09/02 00:00 | Eastern Illinois v Northern Illinois | W | 27-34 |
| NCAAF Bowl Games | 2021/12/17 23:00 | Coastal Carolina v Northern Illinois | L | 47-41 |
Away History
| NCAAF | 2022/10/15 19:30 | Ohio v Western Michigan | W | 33-14 |
| NCAAF | 2022/10/08 18:00 | Akron v Ohio | W | 34-55 |
| NCAAF | 2022/10/01 19:30 | Ohio v Kent State | L | 24-31 |
| NCAAF | 2022/09/24 18:00 | Fordham v Ohio | W | 52-59 |
| NCAAF | 2022/09/17 18:00 | Ohio v Iowa State | L | 10-43 |
| NCAAF | 2022/09/10 16:00 | Ohio v Penn State | L | 10-46 |
| NCAAF | 2022/09/03 22:00 | Florida Atlantic v Ohio | W | 38-41 |
| NCAAF | 2021/11/26 17:00 | Ohio v Bowling Green | L | 10-21 |