Home History
| England FA Premier Women | 2022/05/01 13:00 | Southampton Women v Cardiff City Women | W | 4-1 |
| England FA Premier Women | 2022/04/27 18:45 | Southampton Women v Oxford Utd Women | D | 3-3 |
| England FA Premier Women | 2022/04/03 13:00 | Ipswich Town Women v Southampton Women | W | 1-2 |
| England FA Premier Women | 2022/03/27 13:00 | Gillingham Women v Southampton Women | W | 0-2 |
| England FA Premier Women | 2022/03/23 19:45 | London Bees Women v Southampton Women | W | 1-2 |
| England FA Premier Women | 2022/03/13 14:00 | Southampton Women v Bridgwater United Women | D | 1-1 |
| England FA Cup Women | 2022/02/27 14:00 | Ipswich Town Women v Southampton Women | D | 0-0 |
| England FA Cup Women | 2022/01/30 13:00 | Southampton Women v Bristol City Women | D | 0-0 |
Away History
| Women’s Friendly | 2022/08/14 10:00 | Charlton Women v West Ham Women | L | 1-2 |
| England Championship Women | 2022/05/01 13:00 | Charlton Women v Durham Women | W | 2-1 |
| England Championship Women | 2022/04/24 11:00 | Blackburn Women v Charlton Women | W | 0-3 |
| England Championship Women | 2022/04/03 13:00 | London City Lionesses Women v Charlton Women | L | 2-0 |
| England Championship Women | 2022/03/27 14:30 | Charlton Women v Crystal Palace Women | L | 0-1 |
| England Championship Women | 2022/03/20 14:00 | Liverpool Women v Charlton Women | D | 0-0 |
| England Championship Women | 2022/03/13 14:00 | Charlton Women v Liverpool Women | L | 0-1 |
| England Championship Women | 2022/03/06 14:00 | Sunderland Women v Charlton Women | L | 2-0 |