| Australia Victoria U21 League | 2022/05/14 05:00 | Melbourne Knights U21 v Port Melbourne U21 | W | 0-1 |
| Australia Victoria U21 League | 2021/02/27 04:00 | Port Melbourne U21 v Melbourne Knights U21 | L | 0-4 |
| Australia Victoria U21 League | 2022/08/12 08:15 | Bentleigh Greens U21 v Port Melbourne U21 | W | 1-2 |
| Australia Victoria U21 League | 2022/07/30 09:30 | Port Melbourne U21 v South Melbourne U21 | L | 2-3 |
| Australia Victoria U21 League | 2022/07/23 02:15 | Avondale U21 v Port Melbourne U21 | L | 1-0 |
| Australia Victoria U21 League | 2022/07/16 09:30 | Port Melbourne U21 v Dandenong City U21 | W | 5-2 |
| Australia Victoria U21 League | 2022/07/09 09:30 | Port Melbourne U21 v Heidelberg Utd U21 | W | 3-1 |
| Australia Victoria U21 League | 2022/07/02 06:00 | Altona Magic U21 v Port Melbourne U21 | W | 0-4 |
| Australia Victoria U21 League | 2022/06/25 09:30 | Port Melbourne U21 v Oakleigh Cannons U21 | L | 0-1 |
| Australia Victoria U21 League | 2022/06/18 07:00 | Dandenong Thunder U21 v Port Melbourne U21 | W | 2-4 |
| Australia Victoria U21 League | 2022/08/13 05:00 | Melbourne Knights U21 v Altona Magic U21 | L | 0-1 |
| Australia Victoria U21 League | 2022/08/09 09:00 | Melbourne Knights U21 v Green Gully U21 | L | 1-4 |
| Australia Victoria U21 League | 2022/07/29 08:30 | Oakleigh Cannons U21 v Melbourne Knights U21 | W | 1-4 |
| Australia Victoria U21 League | 2022/07/23 05:00 | Melbourne Knights U21 v Dandenong Thunder U21 | W | 2-1 |
| Australia Victoria U21 League | 2022/07/16 02:30 | Eastern Lions U21 v Melbourne Knights U21 | L | 3-1 |
| Australia Victoria U21 League | 2022/07/02 06:00 | Hume City U21 v Melbourne Knights U21 | L | 3-0 |
| Australia Victoria U21 League | 2022/06/25 05:00 | Melbourne Knights U21 v St Albans Saints U21 | D | 1-1 |
| Australia Victoria U21 League | 2022/06/19 03:00 | Heidelberg Utd U21 v Melbourne Knights U21 | W | 1-4 |