London Irish 28-26 Northampton 2022-09-27 18:45
Stadium: Brentford Community Stadium
Referee: Dan Jones
Head to Head
| Premiership Rugby | 2022/09/17 13:00 | Northampton v London Irish | L | 38-22 |
| Premiership Rugby | 2022/03/26 15:00 | London Irish v Northampton | L | 22-42 |
| Premiership Rugby Cup | 2021/11/13 15:30 | Northampton v London Irish | W | 26-36 |
| Premiership Rugby | 2021/10/02 13:00 | Northampton v London Irish | L | 23-21 |
| Premiership Rugby | 2021/04/16 18:45 | Northampton v London Irish | L | 44-26 |
| Premiership Rugby | 2020/08/22 13:00 | London Irish v Northampton | L | 3-27 |
| Premiership Rugby | 2020/01/24 19:45 | Northampton v London Irish | W | 16-20 |
| Premiership Rugby | 2018/02/17 15:00 | Northampton v London Irish | L | 25-17 |
Home History
| Premiership Rugby | 2022/09/24 14:00 | Bristol v London Irish | L | 40-36 |
| Premiership Rugby Cup | 2022/09/21 18:45 | Harlequins v London Irish | W | 26-30 |
| Premiership Rugby | 2022/09/17 13:00 | Northampton v London Irish | L | 38-22 |
| Premiership Rugby | 2022/05/21 14:00 | Bath v London Irish | L | 27-24 |
| Premiership Rugby Cup | 2022/05/17 18:45 | London Irish v Worcester Warriors | D | 25-25 |
| European Rugby Challenge Cup | 2022/05/08 11:30 | Toulon v London Irish | L | 19-18 |
| Premiership Rugby | 2022/05/01 14:00 | London Irish v Wasps | D | 42-42 |
| Premiership Rugby Cup | 2022/04/26 18:45 | London Irish v Leicester | W | 59-20 |
Away History
| Premiership Rugby | 2022/09/24 14:00 | Northampton v Leicester | L | 21-41 |
| Premiership Rugby | 2022/09/17 13:00 | Northampton v London Irish | W | 38-22 |
| Premiership Rugby | 2022/09/11 14:00 | Sale Sharks v Northampton | L | 29-22 |
| Friendlies | 2022/09/02 18:00 | Ospreys v Northampton | L | 31-24 |
| Premiership Rugby | 2022/06/11 15:30 | Leicester v Northampton | L | 27-14 |
| Premiership Rugby | 2022/06/04 14:00 | Northampton v Newcastle Falcons | W | 65-26 |
| Premiership Rugby | 2022/05/21 16:30 | Saracens v Northampton | L | 42-38 |
| Premiership Rugby | 2022/04/29 18:45 | Northampton v Harlequins | W | 32-31 |