[46] Ajla Tomljanovic 7-5,6-7,6-1 Serena Williams [413] 2022-09-02 23:00
Stadium: Arthur Ashe Stadium Round: 25 Ground: Hardcourt outdoor
Home History
| US Open Women | 2022/08/31 23:00 | Evgeniya Rodina v Ajla Tomljanovic | 6-1,2-6,5-7 |
| US Open Women | 2022/08/29 21:25 | Karolina Muchova v Ajla Tomljanovic | 3-6,6-7 |
| WTA Cincinnati | 2022/08/19 17:30 | Ajla Tomljanovic v Petra Kvitova | 2-6,3-6 |
| WTA Cincinnati | 2022/08/18 21:50 | Ajla Tomljanovic v Veronika Kudermetova | 3-6,7-6,6-3 |
| WTA Cincinnati | 2022/08/18 02:50 | Paula Badosa v Ajla Tomljanovic | 7-6,0-6,2-6 |
| WTA Cincinnati | 2022/08/16 00:35 | Taylor Townsend v Ajla Tomljanovic | 4-6,6-3,5-7 |
| WTA Cincinnati | 2022/08/14 19:20 | Ajla Tomljanovic v Nuria Parrizas-Diaz | 4-6,6-1,6-1 |
| WTA Cincinnati | 2022/08/13 20:05 | Clara Tauson v Ajla Tomljanovic | 2-6,3-6 |
Away History
| US Open Women | 2022/08/31 23:00 | Serena Williams v Anett Kontaveit | 7-6,2-6,6-2 |
| US Open Women | 2022/08/29 23:00 | Danka Kovinic v Serena Williams | 3-6,3-6 |
| WTA Cincinnati | 2022/08/16 23:00 | Serena Williams v Emma Raducanu | 4-6,0-6 |
| WTA Toronto | 2022/08/10 23:00 | Belinda Bencic v Serena Williams | 6-2,6-4 |
| WTA Toronto | 2022/08/08 16:20 | Nuria Parrizas-Diaz v Serena Williams | 3-6,4-6 |
| Wimbledon Women | 2022/06/28 18:05 | Serena Williams v Harmony Tan | 5-7,6-1,6-7 |
| French Open Women | 2021/06/06 15:45 | Serena Williams v Elena Rybakina | 3-6,5-7 |
| French Open Women | 2021/06/04 14:05 | Serena Williams v Danielle Rose Collins | 6-4,6-4 |