Stadium: Selby Stadium Round: 1
| NCAAF | 2021/11/13 18:30 | Ohio Northern Polar Bears v Heidelberg Student Princes | L | 32-33 |
| NCAAF | 2021/11/06 17:30 | Ohio Northern Polar Bears v Baldwin Wallace Yellow Jackets | L | 14-17 |
| NCAAF | 2021/10/30 18:00 | Mount Union v Ohio Northern Polar Bears | L | 42-35 |
| NCAAF | 2021/10/23 17:30 | Ohio Northern Polar Bears v Capital Crusaders | L | 28-35 |
| NCAAF | 2021/10/16 18:00 | John Carroll Blue Streaks v Ohio Northern Polar Bears | L | 27-17 |
| NCAAF | 2021/10/02 17:30 | Ohio Northern Polar Bears v Marietta Pioneers | W | 34-33 |
| NCAAF | 2021/09/25 17:30 | Ohio Northern Polar Bears v Otterbein Cardinals | W | 56-7 |
| NCAAF | 2021/09/18 19:00 | Wilmington Quakers v Ohio Northern Polar Bears | W | 27-62 |
| NCAAF | 2021/11/13 18:00 | Albion Britons v Alma College Scots | L | 34-7 |
| NCAAF | 2021/11/06 17:00 | Alma College Scots v Trine Thunder | L | 23-37 |
| NCAAF | 2021/10/30 17:00 | Alma College Scots v Hope Flying Dutchmen | L | 3-27 |
| NCAAF | 2021/10/16 21:00 | Adrian Bulldogs v Alma College Scots | L | 36-21 |
| NCAAF | 2021/10/09 17:00 | Kalamazoo Hornets v Alma College Scots | W | 3-28 |
| NCAAF | 2021/10/02 18:00 | Alma College Scots v Olivet Comets | L | 10-33 |
| NCAAF | 2021/09/25 18:00 | Martin Luther Knights v Alma College Scots | W | 27-35 |
| NCAAF | 2021/09/18 22:00 | Alma College Scots v Anderson Ravens | W | 51-2 |