Stadium: Ratliff Stadium Round: 1
| NCAAF | 2021/11/13 19:00 | Midwestern State University Mustangs v Texas-Permian Basin Falcons | L | 36-30 |
| NCAAF | 2021/11/06 19:00 | Texas-Permian Basin Falcons v Texas AM Kingsville Javelinas | L | 22-29 |
| NCAAF | 2021/10/30 21:00 | Texas A&M-Commerce v Texas-Permian Basin Falcons | L | 41-0 |
| NCAAF | 2021/10/23 23:00 | Texas-Permian Basin Falcons v Eastern New Mexico University Greyhounds | W | 44-21 |
| NCAAF | 2021/10/16 23:00 | Angelo State Univeristy Rams v Texas-Permian Basin Falcons | L | 34-14 |
| NCAAF | 2021/10/09 23:00 | Texas-Permian Basin Falcons v Lincoln Oaklanders | W | 75-0 |
| NCAAF | 2021/09/26 00:00 | Western New Mexico Mustangs v Texas-Permian Basin Falcons | W | 19-27 |
| NCAAF | 2021/09/18 23:00 | Abilene Christian v Texas-Permian Basin Falcons | L | 34-9 |
| NCAAF | 2021/11/13 19:00 | Southwest Baptist University Bearcats v Missouri S&t Miners | L | 41-42 |
| NCAAF | 2021/11/06 18:00 | Quincy v Southwest Baptist University Bearcats | W | 31-47 |
| NCAAF | 2021/10/30 18:00 | Southwest Baptist University Bearcats v McKendree | L | 42-45 |
| NCAAF | 2021/10/23 18:00 | Lindenwood v Southwest Baptist University Bearcats | L | 48-24 |
| NCAAF | 2021/10/16 18:00 | Southwest Baptist University Bearcats v Truman Bulldogs | W | 27-21 |
| NCAAF | 2021/10/09 20:00 | William Jewell College Cardinals v Southwest Baptist University Bearcats | W | 10-55 |
| NCAAF | 2021/10/02 18:00 | Southwest Baptist University Bearcats v Indianapolis Greyhounds | L | 10-77 |
| NCAAF | 2021/09/25 22:00 | Lake Erie v Southwest Baptist University Bearcats | W | 20-28 |