Stadium: West Virginia State Lakin Field Round: 1
| NCAAF | 2021/09/04 17:00 | Shippensburg Raiders v West Virginia State Yellow Jackets | L | 25-17 |
| NCAAF | 2021/11/13 17:00 | West Virginia State Yellow Jackets v University of Charleston Golden Eagles | L | 13-38 |
| NCAAF | 2021/11/06 18:00 | West Liberty Hilltoppers v West Virginia State Yellow Jackets | W | 28-33 |
| NCAAF | 2021/10/30 17:00 | West Virginia State Yellow Jackets v Glenville State Pioneers | W | 38-27 |
| NCAAF | 2021/10/23 17:00 | Concord University Mountain Lions v West Virginia State Yellow Jackets | W | 32-34 |
| NCAAF | 2021/10/16 22:00 | West Virginia State Yellow Jackets v Unc Pembroke Braves | L | 13-14 |
| NCAAF | 2021/10/09 17:30 | W. Virginia Bobcats v West Virginia State Yellow Jackets | W | 3-38 |
| NCAAF | 2021/10/02 23:00 | West Virginia State Yellow Jackets v Alderson Broaddus Battlers | W | 45-13 |
| NCAAF | 2021/09/25 16:00 | Notre Dame Falcons v West Virginia State Yellow Jackets | L | 38-14 |
| NCAAF | 2021/11/13 18:00 | Shippensburg Raiders v Mercyhurst | W | 17-13 |
| NCAAF | 2021/11/06 17:00 | Shippensburg Raiders v Lock Haven | W | 52-14 |
| NCAAF | 2021/10/30 17:05 | East Stroudsburg Warriors v Shippensburg Raiders | W | 23-24 |
| NCAAF | 2021/10/23 17:00 | Shippensburg Raiders v Millersville University of Pennsylvania Marauders | W | 38-7 |
| NCAAF | 2021/10/16 21:00 | Kutztown Golden Bears v Shippensburg Raiders | L | 20-3 |
| NCAAF | 2021/10/09 17:00 | Shippensburg Raiders v West Chester Golden Rams | W | 34-18 |
| NCAAF | 2021/10/02 16:00 | Shepherd Rams v Shippensburg Raiders | L | 59-27 |
| NCAAF | 2021/09/25 17:00 | Shippensburg Raiders v Bloomsburg Huskies | W | 51-7 |