Stadium: Stisser Field at the Knosher Bowl Round: 1
| NCAAF | 2021/11/13 18:00 | Monmouth Scots v Knox Prairie Fire | L | 38-7 |
| NCAAF | 2021/11/06 18:00 | Knox Prairie Fire v Cornell Rams | L | 34-35 |
| NCAAF | 2021/10/30 18:00 | Knox Prairie Fire v Lawrence Vikings | W | 56-28 |
| NCAAF | 2021/10/23 18:00 | Illinois College Blueboys v Knox Prairie Fire | L | 27-20 |
| NCAAF | 2021/10/16 18:00 | Grinnell Pioneers v Knox Prairie Fire | W | 28-49 |
| NCAAF | 2021/10/09 18:00 | Knox Prairie Fire v Beloit Buccaneers | W | 42-0 |
| NCAAF | 2021/10/02 19:00 | Chicago Maroons v Knox Prairie Fire | L | 45-10 |
| NCAAF | 2021/09/18 19:00 | Knox Prairie Fire v Lake Forest Foresters | L | 10-41 |
| NCAAF | 2021/11/13 18:00 | Crown Storm v Westminster Blue Jays | W | 35-56 |
| NCAAF | 2021/11/06 17:00 | Westminster Blue Jays v Martin Luther Knights | L | 14-28 |
| NCAAF | 2021/10/30 17:00 | Westminster Blue Jays v Finlandia Lions | W | 42-32 |
| NCAAF | 2021/10/23 17:00 | Northwestern Eagles v Westminster Blue Jays | L | 45-28 |
| NCAAF | 2021/10/16 18:00 | Westminster Blue Jays v Greenville Panthers | L | 14-42 |
| NCAAF | 2021/10/02 17:00 | Minnesota Morris Cougars v Westminster Blue Jays | L | 38-35 |
| NCAAF | 2021/09/25 18:00 | Westminster Blue Jays v Rhodes Lynx | L | 7-47 |
| NCAAF | 2021/09/18 18:00 | Sewanee Tigers v Westminster Blue Jays | W | 29-30 |