Stadium: Fred Selfe Stadium Round: 1
| NCAAF | 2021/11/13 18:00 | Emory And Henry Wasps v Ferrum Panthers | W | 41-23 |
| NCAAF | 2021/11/06 17:00 | Guilford Quakers v Emory And Henry Wasps | W | 13-66 |
| NCAAF | 2021/10/30 17:00 | Emory And Henry Wasps v Washington And Lee Generals | L | 28-30 |
| NCAAF | 2021/10/23 17:00 | Shenandoah Hornets v Emory And Henry Wasps | L | 9-7 |
| NCAAF | 2021/10/16 17:00 | Emory And Henry Wasps v Hampden Sydney Tigers | W | 37-13 |
| NCAAF | 2021/10/09 17:00 | Randolph Macon Yellow Jackets v Emory And Henry Wasps | L | 34-31 |
| NCAAF | 2021/09/25 17:00 | Emory And Henry Wasps v Bridgewater Eagles | W | 38-17 |
| NCAAF | 2021/09/18 17:00 | Emory And Henry Wasps v The Apprentice School Builders | W | 63-7 |
| NCAAF | 2021/11/13 18:00 | Concord University Mountain Lions v Unc Pembroke Braves | W | 28-25 |
| NCAAF | 2021/11/06 18:00 | Alderson Broaddus Battlers v Concord University Mountain Lions | W | 10-23 |
| NCAAF | 2021/10/30 16:00 | Wheeling v Concord University Mountain Lions | L | 15-14 |
| NCAAF | 2021/10/23 17:00 | Concord University Mountain Lions v West Virginia State Yellow Jackets | L | 32-34 |
| NCAAF | 2021/10/16 16:00 | University of Charleston Golden Eagles v Concord University Mountain Lions | L | 48-3 |
| NCAAF | 2021/10/09 17:00 | Concord University Mountain Lions v West Liberty Hilltoppers | W | 20-16 |
| NCAAF | 2021/10/02 18:00 | Fairmont State v Concord University Mountain Lions | L | 31-27 |
| NCAAF | 2021/09/25 17:00 | Concord University Mountain Lions v Frostburg State | L | 23-42 |