Stadium: John Coughlin Memorial Field Round: 1
| NCAAF | 2021/09/03 23:00 | Wpi Engineers v Worcester State Lancers | L | 38-20 |
| NCAAF | 2019/09/06 23:00 | Wpi Engineers v Worcester State Lancers | L | 51-0 |
| NCAAF | 2021/11/13 17:00 | Worcester State Lancers v Framingham State Rams | L | 21-40 |
| NCAAF | 2021/11/06 16:00 | Westfield State Owls v Worcester State Lancers | W | 30-33 |
| NCAAF | 2021/10/30 16:00 | Worcester State Lancers v Western Connecticut Colonials | L | 30-56 |
| NCAAF | 2021/10/23 17:00 | Plymouth State Panthers v Worcester State Lancers | L | 42-14 |
| NCAAF | 2021/10/16 16:00 | Massachusetts Maritime Buccaneers v Worcester State Lancers | W | 24-28 |
| NCAAF | 2021/10/09 16:00 | Worcester State Lancers v Bridgewater State Bears | L | 13-49 |
| NCAAF | 2021/09/25 16:00 | Umass Dartmouth Corsairs v Worcester State Lancers | L | 52-7 |
| NCAAF | 2021/09/18 18:30 | Worcester State Lancers v Fitchburg State Falcons | W | 38-35 |
| NCAAF | 2021/11/13 18:00 | Mit Engineers v Wpi Engineers | L | 38-10 |
| NCAAF | 2021/11/06 16:00 | Wpi Engineers v Coast Guard Bears | W | 38-6 |
| NCAAF | 2021/10/30 16:00 | Norwich Cadets v Wpi Engineers | W | 2-28 |
| NCAAF | 2021/10/23 16:00 | Wpi Engineers v Springfield Pride | L | 17-46 |
| NCAAF | 2021/10/09 16:00 | Wpi Engineers v Catholic Cardinals | L | 7-30 |
| NCAAF | 2021/10/02 17:00 | Merchant Marine Mariners v Wpi Engineers | L | 31-28 |
| NCAAF | 2021/09/25 18:00 | Montclair State Red Hawks v Wpi Engineers | L | 31-10 |
| NCAAF | 2021/09/18 18:30 | Wpi Engineers v Rpi Engineers | L | 10-24 |