Stadium: Luther "Nick" Jeralds Stadium Round: 1
| NCAAF | 2021/11/06 18:00 | Fayetteville State Broncos v Winston-Salem State | W | 10-3 |
| NCAAF | 2021/10/30 18:00 | Fayetteville State Broncos v Livingstone C. BB | W | 34-0 |
| NCAAF | 2021/10/23 17:00 | St Augustines Falcons v Fayetteville State Broncos | W | 12-40 |
| NCAAF | 2021/10/16 18:00 | Fayetteville State Broncos v Johnson C Smith GB | W | 55-12 |
| NCAAF | 2021/10/09 17:00 | Shaw Bears v Fayetteville State Broncos | W | 12-15 |
| NCAAF | 2021/10/02 23:00 | Fayetteville State Broncos v Lincoln University | W | 46-9 |
| NCAAF | 2021/09/25 23:00 | Fayetteville State Broncos v Virginia State Trojans | W | 28-14 |
| NCAAF | 2021/09/11 22:00 | Wingate Bulldogs v Fayetteville State Broncos | L | 40-21 |
| NCAAF | 2021/11/13 18:00 | Concord University Mountain Lions v Unc Pembroke Braves | L | 28-25 |
| NCAAF | 2021/11/06 16:00 | Unc Pembroke Braves v Notre Dame Falcons | L | 7-45 |
| NCAAF | 2021/10/30 16:00 | West Liberty Hilltoppers v Unc Pembroke Braves | W | 17-27 |
| NCAAF | 2021/10/23 18:00 | Unc Pembroke Braves v University of Charleston Golden Eagles | W | 21-14 |
| NCAAF | 2021/10/16 22:00 | West Virginia State Yellow Jackets v Unc Pembroke Braves | W | 13-14 |
| NCAAF | 2021/10/09 16:00 | Unc Pembroke Braves v Wheeling Jesuit | W | 34-28 |
| NCAAF | 2021/10/02 17:00 | Frostburg State v Unc Pembroke Braves | L | 51-21 |
| NCAAF | 2021/09/25 17:00 | Unc Pembroke Braves v Fairmont State | L | 27-30 |