| Colombia Regional League | 2022/08/29 14:15 | Lula FC v Sol de Oriente | L | 2-1 |
| Colombia Regional League | 2022/08/21 21:19 | Sol de Oriente v Real San Jeronimo | W | 3-0 |
| Colombia Regional League | 2022/08/18 16:07 | Sol de Oriente v Aguilas Doradas Reserves | D | 2-2 |
| Colombia Regional League | 2022/07/13 17:12 | Sol de Oriente v Total Soccer FC | D | 2-2 |
| Colombia Regional League | 2022/07/06 17:00 | Ferrovalvulas FC v Sol de Oriente | W | 2-3 |
| Colombia Regional League | 2022/06/15 17:18 | Sol de Oriente v Politecnico J.I.C. | D | 0-0 |
| Colombia Regional League | 2022/05/30 17:23 | Sol de Oriente v Real Santuario | W | 2-1 |
| Colombia Regional League | 2022/05/25 17:00 | Sol de Oriente v Envigado FC Reserves | L | 0-2 |
| Colombia Regional League | 2022/08/30 15:00 | Medellin City FC v FC Leones Reserves | W | 4-0 |
| Colombia Regional League | 2022/08/15 15:13 | Real Santuario v Medellin City FC | L | 4-0 |
| Colombia Regional League | 2022/08/02 19:17 | Medellin City FC v Universidad de Antioquia | L | 0-1 |
| Colombia Regional League | 2022/07/11 16:00 | CD Gallegol v Medellin City FC | W | 2-4 |
| Colombia Regional League | 2022/07/05 15:23 | Medellin City FC v E.D.P IND. Medellin | W | 4-1 |
| Colombia Regional League | 2022/06/16 12:19 | Molino Viejo v Medellin City FC | L | 3-1 |
| Colombia Regional League | 2022/05/27 15:00 | Club Deportivo La Chalaca v Medellin City FC | L | 4-1 |
| Colombia Regional League | 2022/05/24 15:00 | Medellin City FC v Estudiantes de Medellin | W | 5-2 |