Stadium: George Williams Athletic Complex Round: 1
| NCAAF | 2022/09/01 22:00 | Tusculum Pioneers v St Augustines Falcons | L | 70-13 |
| NCAAF | 2021/11/06 17:00 | St Augustines Falcons v Shaw Bears | W | 21-17 |
| NCAAF | 2021/10/30 17:00 | Johnson C Smith GB v St Augustines Falcons | L | 34-13 |
| NCAAF | 2021/10/23 17:00 | St Augustines Falcons v Fayetteville State Broncos | L | 12-40 |
| NCAAF | 2021/10/16 17:30 | Winston-Salem State v St Augustines Falcons | L | 41-0 |
| NCAAF | 2021/10/09 17:30 | Livingstone C. BB v St Augustines Falcons | L | 21-7 |
| NCAAF | 2021/10/02 22:00 | Virginia State Trojans v St Augustines Falcons | L | 33-9 |
| NCAAF | 2021/09/25 17:00 | St Augustines Falcons v Chowan Hawks | L | 12-59 |
| NCAAF | 2022/09/01 23:00 | Gardner Webb v Limestone Saints | L | 56-21 |
| NCAAF | 2021/11/13 21:00 | Limestone Saints v Newberry Wolves | L | 7-42 |
| NCAAF | 2021/11/06 17:00 | Carson–Newman Eagles v Limestone Saints | L | 27-21 |
| NCAAF | 2021/10/30 20:00 | Limestone Saints v Virginia Wise Highland Cavaliers | L | 24-28 |
| NCAAF | 2021/10/23 18:00 | Lenoir Rhyne Bears v Limestone Saints | L | 45-3 |
| NCAAF | 2021/10/16 20:00 | Limestone Saints v Mars Hill Lions | L | 3-32 |
| NCAAF | 2021/10/09 17:00 | Limestone Saints v Wingate Bulldogs | L | 17-35 |
| NCAAF | 2021/09/25 23:00 | Limestone Saints v Barton Bulldogs | L | 7-45 |