Stadium: Younts Stadium Round: 1
| NCAAF | 2021/09/11 22:00 | Newberry Wolves v North Greenville Crusaders | W | 14-24 |
| NCAAF | 2019/09/05 23:00 | North Greenville Crusaders v Newberry Wolves | W | 17-7 |
| NCAAF | 2022/09/01 23:00 | Furman v North Greenville Crusaders | L | 52-0 |
| NCAAF | 2021/11/13 17:00 | North Greenville Crusaders v Shorter | W | 56-0 |
| NCAAF | 2021/11/06 19:00 | Valdosta State v North Greenville Crusaders | L | 31-21 |
| NCAAF | 2021/10/30 16:00 | North Greenville Crusaders v West Alabama Tigers | L | 14-31 |
| NCAAF | 2021/10/23 22:00 | West Georgia v North Greenville Crusaders | L | 34-12 |
| NCAAF | 2021/10/16 19:00 | Delta State v North Greenville Crusaders | W | 34-42 |
| NCAAF | 2021/10/09 23:00 | North Greenville Crusaders v West Florida | L | 10-52 |
| NCAAF | 2021/10/02 19:00 | North Greenville Crusaders v Mississippi College Choctaws | L | 21-42 |
| NCAAF | 2022/09/03 22:00 | Newberry Wolves v Allen Yellow Jackets | W | 40-6 |
| NCAAF | 2021/11/27 18:00 | Bowie State Bulldogs v Newberry Wolves | L | 13-10 |
| NCAAF | 2021/11/20 18:00 | West Florida v Newberry Wolves | W | 30-33 |
| NCAAF | 2021/11/13 21:00 | Limestone Saints v Newberry Wolves | W | 7-42 |
| NCAAF | 2021/11/06 17:00 | Newberry Wolves v Wingate Bulldogs | W | 41-35 |
| NCAAF | 2021/10/30 17:00 | Erskine Flying Fleet v Newberry Wolves | W | 10-48 |
| NCAAF | 2021/10/23 20:00 | Newberry Wolves v Carson–Newman Eagles | W | 34-3 |
| NCAAF | 2021/10/16 21:00 | Newberry Wolves v Catawba College | W | 14-7 |