Stadium: First Security Stadium Round: 1
| NCAAF | 2021/09/11 23:00 | Southeastern Oklahoma State Savage Storm v Harding Bisons | L | 32-31 |
| NCAAF | 2019/11/09 20:00 | Southeastern Oklahoma State Savage Storm v Harding Bisons | W | 14-35 |
| NCAAF | 2018/11/03 19:00 | Harding Bisons v Southeastern Oklahoma State Savage Storm | W | 24-10 |
| NCAAF | 2022/09/01 23:00 | East Central Tigers v Harding Bisons | W | 12-29 |
| NCAAF | 2021/11/27 19:00 | Harding Bisons v NW Missouri State | L | 9-28 |
| NCAAF | 2021/11/20 19:00 | Harding Bisons v Washburn Ichabods Football | W | 30-14 |
| NCAAF | 2021/11/13 20:00 | Arkansas Tech Wonder Boys v Harding Bisons | W | 0-31 |
| NCAAF | 2021/11/06 19:00 | Southwestern Oklahoma State Bulldogs v Harding Bisons | W | 7-55 |
| NCAAF | 2021/10/30 19:00 | Northwestern Oklahoma State Rangers v Harding Bisons | W | 14-73 |
| NCAAF | 2021/10/23 20:00 | Harding Bisons v Arkansas Monticello Boll Weevils | W | 64-7 |
| NCAAF | 2021/10/16 19:00 | Henderson State Reddies v Harding Bisons | W | 21-46 |
| NCAAF | 2022/09/01 23:00 | Southeastern Oklahoma State Savage Storm v Arkansas Tech Wonder Boys | W | 41-34 |
| NCAAF | 2021/11/13 20:00 | Southeastern Oklahoma State Savage Storm v East Central Tigers | L | 28-30 |
| NCAAF | 2021/11/06 18:00 | Ouachita Baptist Tigers v Southeastern Oklahoma State Savage Storm | W | 21-35 |
| NCAAF | 2021/10/30 19:00 | Southeastern Oklahoma State Savage Storm v Arkansas Monticello Boll Weevils | W | 34-14 |
| NCAAF | 2021/10/23 23:00 | Oklahoma Baptist Bison v Southeastern Oklahoma State Savage Storm | L | 43-37 |
| NCAAF | 2021/10/16 19:00 | Southeastern Oklahoma State Savage Storm v Northwestern Oklahoma State Rangers | W | 43-10 |
| NCAAF | 2021/10/09 19:30 | Southern Arkansas Muleriders v Southeastern Oklahoma State Savage Storm | W | 24-38 |
| NCAAF | 2021/10/02 19:00 | Southeastern Oklahoma State Savage Storm v Henderson State Reddies | L | 24-27 |