Stadium: Lyle Hare Stadium Round: 1
| NCAAF | 2022/09/02 00:00 | Dickinson State Blue Hawks v Black Hills State | W | 2-17 |
| NCAAF | 2021/11/13 20:00 | Black Hills State v Chadron State Eagles | L | 6-57 |
| NCAAF | 2021/11/06 19:00 | Colorado Mesa University Mavericks v Black Hills State | L | 52-9 |
| NCAAF | 2021/10/30 19:00 | Black Hills State v South Dakota Mines Hardrockers | L | 10-13 |
| NCAAF | 2021/10/23 19:00 | Black Hills State v N. Mexico H. Cowboys | L | 10-24 |
| NCAAF | 2021/10/16 19:00 | Western State Colorado Mountaineers v Black Hills State | L | 44-28 |
| NCAAF | 2021/10/09 19:00 | Black Hills State v Colorado School of Mines | L | 20-41 |
| NCAAF | 2021/10/02 18:00 | Fort Lewis Skyhawks v Black Hills State | W | 17-45 |
| NCAAF | 2022/09/02 00:00 | William Jewell College Cardinals v Colorado Mesa University Mavericks | L | 14-37 |
| NCAAF | 2021/11/13 19:00 | William Jewell College Cardinals v Quincy | L | 17-51 |
| NCAAF | 2021/11/06 18:00 | Indianapolis Greyhounds v William Jewell College Cardinals | L | 45-14 |
| NCAAF | 2021/10/30 18:00 | William Jewell College Cardinals v Lindenwood | L | 10-53 |
| NCAAF | 2021/10/23 19:00 | Truman Bulldogs v William Jewell College Cardinals | L | 52-0 |
| NCAAF | 2021/10/16 18:00 | Missouri S&t Miners v William Jewell College Cardinals | L | 37-16 |
| NCAAF | 2021/10/09 20:00 | William Jewell College Cardinals v Southwest Baptist University Bearcats | L | 10-55 |
| NCAAF | 2021/10/02 18:00 | McKendree v William Jewell College Cardinals | L | 52-10 |