Stadium: Garrison Stadium Round: 1
| NCAAF | 2022/09/01 22:00 | Chowan Hawks v Barton Bulldogs | L | 3-17 |
| NCAAF | 2021/11/06 17:00 | Chowan Hawks v Lincoln University | W | 28-12 |
| NCAAF | 2021/10/30 18:00 | Virginia State Trojans v Chowan Hawks | W | 30-38 |
| NCAAF | 2021/10/23 17:30 | Elizabeth City State Vikings v Chowan Hawks | L | 32-28 |
| NCAAF | 2021/10/16 17:00 | Chowan Hawks v Virginia Union Panthers | L | 31-38 |
| NCAAF | 2021/10/09 17:00 | Chowan Hawks v Bowie State Bulldogs | L | 3-14 |
| NCAAF | 2021/10/02 22:00 | Chowan Hawks v Winston-Salem State | W | 73-7 |
| NCAAF | 2021/09/25 17:00 | St Augustines Falcons v Chowan Hawks | W | 12-59 |
| NCAAF | 2022/09/01 22:00 | Tusculum Pioneers v St Augustines Falcons | W | 70-13 |
| NCAAF | 2021/11/13 18:30 | Tusculum Pioneers v Carson–Newman Eagles | W | 48-13 |
| NCAAF | 2021/11/06 17:00 | Mars Hill Lions v Tusculum Pioneers | L | 20-7 |
| NCAAF | 2021/10/30 17:00 | Catawba College v Tusculum Pioneers | L | 31-28 |
| NCAAF | 2021/10/23 18:00 | Tusculum Pioneers v Barton Bulldogs | W | 41-17 |
| NCAAF | 2021/10/16 17:30 | Tusculum Pioneers v Virginia Wise Highland Cavaliers | W | 37-21 |
| NCAAF | 2021/10/09 18:00 | Lenoir Rhyne Bears v Tusculum Pioneers | L | 38-31 |
| NCAAF | 2021/10/02 22:00 | Wingate Bulldogs v Tusculum Pioneers | L | 43-35 |