Stadium: O'Harra Stadium Round: 1
| NCAAF | 2022/09/01 23:00 | Missouri S&t Miners v South Dakota Mines Hardrockers | W | 20-43 |
| NCAAF | 2021/11/13 19:00 | South Dakota Mines Hardrockers v Colorado Mesa University Mavericks | L | 10-13 |
| NCAAF | 2021/11/06 18:00 | N. Mexico H. Cowboys v South Dakota Mines Hardrockers | W | 17-40 |
| NCAAF | 2021/10/30 19:00 | Black Hills State v South Dakota Mines Hardrockers | W | 10-13 |
| NCAAF | 2021/10/23 18:00 | South Dakota Mines Hardrockers v Western State Colorado Mountaineers | L | 21-42 |
| NCAAF | 2021/10/16 18:00 | Colorado School of Mines v South Dakota Mines Hardrockers | L | 44-24 |
| NCAAF | 2021/10/09 18:00 | South Dakota Mines Hardrockers v Fort Lewis Skyhawks | W | 42-7 |
| NCAAF | 2021/10/02 19:00 | Adams State Grizzlies v South Dakota Mines Hardrockers | W | 42-45 |
| NCAAF | 2022/09/03 17:00 | Truman Bulldogs v Davenport Panthers | L | 19-20 |
| NCAAF | 2021/11/13 18:00 | Truman Bulldogs v Indianapolis Greyhounds | L | 10-13 |
| NCAAF | 2021/11/06 18:00 | McKendree v Truman Bulldogs | W | 13-44 |
| NCAAF | 2021/10/30 17:00 | Truman Bulldogs v Quincy | W | 49-28 |
| NCAAF | 2021/10/23 19:00 | Truman Bulldogs v William Jewell College Cardinals | W | 52-0 |
| NCAAF | 2021/10/16 18:00 | Southwest Baptist University Bearcats v Truman Bulldogs | L | 27-21 |
| NCAAF | 2021/10/09 18:00 | Missouri S&t Miners v Truman Bulldogs | W | 21-38 |
| NCAAF | 2021/10/02 23:00 | Truman Bulldogs v Lindenwood | L | 21-31 |