Head to Head
| Ghana Premier League | 2022/11/12 15:00 | Medeama SC v Asante Kotoko | W | 0-1 |
| Ghana Premier League | 2022/05/29 15:00 | Medeama SC v Asante Kotoko | W | 0-2 |
| Ghana Premier League | 2022/01/23 15:00 | Asante Kotoko v Medeama SC | W | 1-0 |
| Ghana Premier League | 2021/04/24 15:00 | Asante Kotoko v Medeama SC | L | 1-2 |
| Ghana Premier League | 2020/12/27 15:00 | Medeama SC v Asante Kotoko | D | 1-1 |
| Ghana Premier League | 2020/01/15 15:00 | Medeama SC v Asante Kotoko | L | 1-0 |
| Ghana Premier League | 2018/03/28 15:00 | Medeama SC v Asante Kotoko | L | 1-0 |
| Ghana FA Cup | 2017/10/02 15:00 | Asante Kotoko v Medeama SC | W | 1-0 |
Home History
| Ghana Premier League | 2023/03/18 15:00 | Samartex v Asante Kotoko | W | 1-2 |
| Ghana Premier League | 2023/03/05 15:00 | Hearts of Oak v Asante Kotoko | L | 1-0 |
| Ghana Premier League | 2023/03/01 15:00 | Asante Kotoko v Bechem FC | W | 1-0 |
| Ghana FA Cup | 2023/02/26 15:00 | Aduana Stars v Asante Kotoko | L | 1-0 |
| Ghana Premier League | 2023/02/18 15:00 | Nsoatreman FC v Asante Kotoko | D | 0-0 |
| Ghana Premier League | 2023/02/12 15:00 | Dreams v Asante Kotoko | L | 2-0 |
| Ghana Premier League | 2023/02/06 18:00 | Asante Kotoko v Accra Lions FC | W | 4-0 |
| Ghana Premier League | 2023/02/02 15:00 | Karela United FC v Asante Kotoko | L | 1-0 |
Away History
| Ghana Premier League | 2023/03/19 15:00 | Medeama SC v Great Olympics | W | 2-0 |
| Ghana Premier League | 2023/03/12 15:00 | Aduana Stars v Medeama SC | L | 1-0 |
| Ghana Premier League | 2023/03/05 15:00 | Medeama SC v Berekum Chelsea | W | 1-0 |
| Ghana Premier League | 2023/03/01 18:45 | Real Tamale United v Medeama SC | D | 1-1 |
| Ghana Premier League | 2023/02/17 15:00 | Medeama SC v Legon Cities FC | W | 2-0 |
| Ghana Premier League | 2023/02/12 15:00 | Tamale City v Medeama SC | D | 0-0 |
| Ghana Premier League | 2023/02/05 15:00 | Medeama SC v Samartex | W | 2-0 |
| Ghana Premier League | 2023/02/01 15:00 | King Faisal v Medeama SC | W | 2-3 |