Stadium: Superior Dome Round: 1
| NCAAF | 2021/09/04 18:00 | McKendree v Northern Michigan Wildcats | W | 20-27 |
| NCAAF | 2019/09/07 17:00 | Northern Michigan Wildcats v McKendree | W | 30-9 |
| NCAAF | 2018/09/01 18:00 | McKendree v Northern Michigan Wildcats | L | 34-28 |
| NCAAF | 2021/11/13 18:00 | Northern Michigan Wildcats v Northwood Timberwolves | W | 34-26 |
| NCAAF | 2021/11/06 17:00 | Saginaw Valley State Cardinals v Northern Michigan Wildcats | L | 33-21 |
| NCAAF | 2021/10/30 17:00 | Ferris State v Northern Michigan Wildcats | L | 44-24 |
| NCAAF | 2021/10/23 17:00 | Northern Michigan Wildcats v Grand Valley State | L | 24-28 |
| NCAAF | 2021/10/16 16:00 | Northern Michigan Wildcats v Michigan Technological University Huskies | L | 14-21 |
| NCAAF | 2021/10/09 16:00 | Davenport Panthers v Northern Michigan Wildcats | L | 18-13 |
| NCAAF | 2021/10/02 20:00 | Northern Michigan Wildcats v Wayne State Warriors Football | W | 26-19 |
| NCAAF | 2021/09/25 17:00 | Northwood Timberwolves v Northern Michigan Wildcats | L | 37-20 |
| NCAAF | 2021/11/13 19:00 | Lindenwood v McKendree | L | 45-30 |
| NCAAF | 2021/11/06 18:00 | McKendree v Truman Bulldogs | L | 13-44 |
| NCAAF | 2021/10/30 18:00 | Southwest Baptist University Bearcats v McKendree | W | 42-45 |
| NCAAF | 2021/10/23 18:00 | McKendree v Missouri S&t Miners | L | 31-37 |
| NCAAF | 2021/10/16 20:00 | Quincy v McKendree | W | 48-51 |
| NCAAF | 2021/10/09 22:00 | Indianapolis Greyhounds v McKendree | L | 57-28 |
| NCAAF | 2021/10/02 18:00 | McKendree v William Jewell College Cardinals | W | 52-10 |
| NCAAF | 2021/09/25 18:00 | Walsh U. Cavaliers v McKendree | W | 10-24 |