Stadium: Taylor Field Round: 1
| NCAAF | 2021/11/13 18:00 | Rockford Regents v Lakeland Muskies | W | 28-56 |
| NCAAF | 2021/11/06 18:00 | Lakeland Muskies v Aurora Spartans | L | 20-38 |
| NCAAF | 2021/10/30 18:00 | Eureka Red Devils v Lakeland Muskies | W | 16-45 |
| NCAAF | 2021/10/23 23:00 | Lakeland Muskies v Concordia Wisconsin Falcons | W | 49-32 |
| NCAAF | 2021/10/16 19:15 | Concordia Chicago Cougars v Lakeland Muskies | W | 7-63 |
| NCAAF | 2021/10/09 18:00 | Benedictine Eagles v Lakeland Muskies | L | 54-40 |
| NCAAF | 2021/09/25 23:00 | Lakeland Muskies v St Norbert Green Knights | W | 40-8 |
| NCAAF | 2021/09/18 18:00 | Lakeland Muskies v Wisconsin Lutheran Warriors | W | 56-7 |
| NCAAF | 2021/11/13 18:00 | Beloit Buccaneers v Illinois College Blueboys | W | 3-21 |
| NCAAF | 2021/11/06 18:00 | Illinois College Blueboys v Grinnell Pioneers | W | 55-24 |
| NCAAF | 2021/10/30 18:00 | Cornell Rams v Illinois College Blueboys | W | 7-39 |
| NCAAF | 2021/10/23 18:00 | Illinois College Blueboys v Knox Prairie Fire | W | 27-20 |
| NCAAF | 2021/10/16 18:00 | Lawrence Vikings v Illinois College Blueboys | W | 37-38 |
| NCAAF | 2021/10/09 18:00 | Illinois College Blueboys v Lake Forest Foresters | L | 13-48 |
| NCAAF | 2021/10/02 18:00 | Ripon Red Hawks v Illinois College Blueboys | L | 24-13 |
| NCAAF | 2021/09/18 18:00 | Illinois College Blueboys v Monmouth Scots | L | 27-37 |