Stadium: Lubbers Stadium Round: 1
| NCAAF | 2021/11/27 18:00 | Ferris State v Grand Valley State | L | 54-20 |
| NCAAF | 2021/11/20 18:00 | Grand Valley State v Lindenwood | W | 20-3 |
| NCAAF | 2021/11/13 18:00 | Grand Valley State v Davenport Panthers | W | 42-0 |
| NCAAF | 2021/11/06 17:00 | Wayne State Warriors Football v Grand Valley State | W | 13-62 |
| NCAAF | 2021/10/30 19:00 | Grand Valley State v Michigan Technological University Huskies | W | 14-9 |
| NCAAF | 2021/10/23 17:00 | Northern Michigan Wildcats v Grand Valley State | W | 24-28 |
| NCAAF | 2021/10/16 23:00 | Grand Valley State v Ferris State | L | 28-35 |
| NCAAF | 2021/10/09 23:00 | Grand Valley State v Northwood Timberwolves | W | 70-9 |
| NCAAF | 2021/12/11 17:00 | Valdosta State v Colorado School of Mines | L | 34-31 |
| NCAAF | 2021/12/04 19:05 | Colorado School of Mines v Angelo State Univeristy Rams | W | 34-26 |
| NCAAF | 2021/11/27 20:00 | Colorado School of Mines v Bemidji State Beavers | W | 55-6 |
| NCAAF | 2021/11/13 19:00 | Colorado School of Mines v Adams State Grizzlies | W | 63-0 |
| NCAAF | 2021/11/06 20:00 | Colorado State Pueblo Thunderwolves v Colorado School of Mines | W | 12-28 |
| NCAAF | 2021/10/30 18:00 | Colorado School of Mines v Chadron State Eagles | W | 34-7 |
| NCAAF | 2021/10/23 19:00 | Colorado Mesa University Mavericks v Colorado School of Mines | L | 26-21 |
| NCAAF | 2021/10/16 18:00 | Colorado School of Mines v South Dakota Mines Hardrockers | W | 44-24 |