Stadium: Robinson-Hale Stadium Round: 1
| NCAAF | 2022/09/03 23:00 | Albany State Golden Rams v Mississippi College Choctaws | L | 28-14 |
| NCAAF | 2021/11/13 18:00 | West Alabama Tigers v Mississippi College Choctaws | W | 24-28 |
| NCAAF | 2021/11/06 19:00 | Delta State v Mississippi College Choctaws | L | 24-21 |
| NCAAF | 2021/10/30 19:00 | Mississippi College Choctaws v West Florida | L | 28-63 |
| NCAAF | 2021/10/23 19:00 | Mississippi College Choctaws v Valdosta State | L | 14-41 |
| NCAAF | 2021/10/16 17:00 | Shorter v Mississippi College Choctaws | W | 7-20 |
| NCAAF | 2021/10/09 19:00 | Mississippi College Choctaws v West Georgia | L | 21-40 |
| NCAAF | 2021/10/02 19:00 | North Greenville Crusaders v Mississippi College Choctaws | W | 21-42 |
| NCAAF | 2022/09/01 23:00 | Valdosta State v Keiser University Seahawks | L | 36-21 |