Stadium: Lewis C. Everett Stadium Round: 1
| NCAAF | 2022/09/10 17:00 | Hampden Sydney Tigers v Widener Pride | L | 27-31 |
| NCAAF | 2022/09/03 17:00 | Wabash Little Giants v Hampden Sydney Tigers | L | 52-48 |
| NCAAF | 2021/11/13 18:00 | Randolph Macon Yellow Jackets v Hampden Sydney Tigers | L | 37-14 |
| NCAAF | 2021/11/06 17:00 | Hampden Sydney Tigers v Bridgewater Eagles | W | 24-14 |
| NCAAF | 2021/10/30 17:00 | The Apprentice School Builders v Hampden Sydney Tigers | W | 21-38 |
| NCAAF | 2021/10/23 17:00 | Hampden Sydney Tigers v Ferrum Panthers | W | 42-28 |
| NCAAF | 2021/10/16 17:00 | Emory And Henry Wasps v Hampden Sydney Tigers | L | 37-13 |
| NCAAF | 2021/10/02 17:00 | Hampden Sydney Tigers v Washington And Lee Generals | L | 30-32 |
| NCAAF | 2022/09/10 17:00 | Gallaudet Bison v Greensboro Pride | L | 31-14 |
| NCAAF | 2022/09/03 16:00 | Greensboro Pride v Guilford Quakers | L | 37-48 |
| NCAAF | 2021/11/13 18:00 | Maryville Scots v Greensboro Pride | L | 49-14 |
| NCAAF | 2021/11/06 16:00 | Greensboro Pride v Methodist Monarchs | L | 14-40 |
| NCAAF | 2021/10/30 17:00 | Lagrange Panthers v Greensboro Pride | L | 29-14 |
| NCAAF | 2021/10/23 16:00 | Greensboro Pride v Huntingdon Hawks | L | 3-42 |
| NCAAF | 2021/10/16 17:00 | Southern Virginia Knights v Greensboro Pride | L | 31-14 |
| NCAAF | 2021/10/09 16:00 | Nc Wesleyan Battling Bishops v Greensboro Pride | L | 21-0 |