Stadium: Abel Stadium Round: 1
| NCAAF | 2021/10/09 18:00 | Nebraska Wesleyan Prairie Wolves v Dubuque Spartans | L | 14-31 |
| NCAAF | 2019/11/16 19:00 | Nebraska Wesleyan Prairie Wolves v Dubuque Spartans | L | 7-42 |
| NCAAF | 2018/10/27 19:00 | Dubuque Spartans v Nebraska Wesleyan Prairie Wolves | L | 54-35 |
| NCAAF | 2022/09/10 18:00 | Mayville State Comets v Nebraska Wesleyan Prairie Wolves | L | 55-48 |
| NCAAF | 2022/09/03 18:00 | Eureka Red Devils v Nebraska Wesleyan Prairie Wolves | W | 6-31 |
| NCAAF | 2021/11/13 19:00 | Nebraska Wesleyan Prairie Wolves v Coe Kohawks | L | 21-53 |
| NCAAF | 2021/11/06 18:00 | Wartburg Knights v Nebraska Wesleyan Prairie Wolves | L | 50-14 |
| NCAAF | 2021/10/30 18:00 | Nebraska Wesleyan Prairie Wolves v Simpson Storm | W | 44-14 |
| NCAAF | 2021/10/16 18:00 | Buena Vista Beavers v Nebraska Wesleyan Prairie Wolves | L | 50-7 |
| NCAAF | 2021/10/09 18:00 | Nebraska Wesleyan Prairie Wolves v Dubuque Spartans | L | 14-31 |
| NCAAF | 2021/10/02 18:00 | Luther Norse v Nebraska Wesleyan Prairie Wolves | W | 21-28 |
| NCAAF | 2022/09/10 23:00 | Dubuque Spartans v Uw-La Crosse Eagles | L | 3-30 |
| NCAAF | 2022/09/03 17:00 | Marietta Pioneers v Dubuque Spartans | L | 14-13 |
| NCAAF | 2021/11/13 19:00 | Dubuque Spartans v Loras Duhawks | W | 17-14 |
| NCAAF | 2021/11/06 18:00 | Central Dutch v Dubuque Spartans | L | 56-7 |
| NCAAF | 2021/10/30 18:00 | Dubuque Spartans v Coe Kohawks | L | 27-34 |
| NCAAF | 2021/10/23 18:00 | Wartburg Knights v Dubuque Spartans | L | 27-7 |
| NCAAF | 2021/10/16 19:00 | Dubuque Spartans v Simpson Storm | W | 41-28 |
| NCAAF | 2021/10/09 18:00 | Nebraska Wesleyan Prairie Wolves v Dubuque Spartans | W | 14-31 |