Stadium: Steele Stadium Round: 1
| NCAAF | 2022/09/11 00:00 | Kentucky Wesleyan v Lake Erie | L | 21-26 |
| NCAAF | 2022/09/03 17:00 | Northwood Timberwolves v Kentucky Wesleyan | L | 55-13 |
| NCAAF | 2021/11/13 18:00 | Kentucky Wesleyan v Ashland Eagles | L | 0-17 |
| NCAAF | 2021/11/06 17:00 | Hillsdale Chargers v Kentucky Wesleyan | L | 31-12 |
| NCAAF | 2021/10/30 19:00 | Lake Erie v Kentucky Wesleyan | L | 38-28 |
| NCAAF | 2021/10/23 16:00 | Kentucky Wesleyan v Tiffin Dragons | L | 28-34 |
| NCAAF | 2021/10/16 17:00 | Walsh U. Cavaliers v Kentucky Wesleyan | W | 13-23 |
| NCAAF | 2021/10/09 17:00 | Findlay Oilers v Kentucky Wesleyan | L | 31-19 |
| NCAAF | 2022/09/10 18:00 | Drake Bulldogs v Missouri S&t Miners | W | 14-17 |
| NCAAF | 2022/09/01 23:00 | Missouri S&t Miners v South Dakota Mines Hardrockers | L | 20-43 |
| NCAAF | 2021/11/13 19:00 | Southwest Baptist University Bearcats v Missouri S&t Miners | W | 41-42 |
| NCAAF | 2021/11/06 18:00 | Missouri S&t Miners v Lindenwood | L | 16-43 |
| NCAAF | 2021/10/30 18:00 | Missouri S&t Miners v Indianapolis Greyhounds | W | 31-28 |
| NCAAF | 2021/10/23 18:00 | McKendree v Missouri S&t Miners | W | 31-37 |
| NCAAF | 2021/10/16 18:00 | Missouri S&t Miners v William Jewell College Cardinals | W | 37-16 |
| NCAAF | 2021/10/09 18:00 | Missouri S&t Miners v Truman Bulldogs | L | 21-38 |