Stadium: SNU Stadium Round: 1
| NCAAF | 2021/09/18 23:00 | East Central Tigers v Southern Nazarene | L | 40-13 |
| NCAAF | 2019/09/21 23:00 | East Central Tigers v Southern Nazarene | L | 45-7 |
| NCAAF | 2018/09/08 23:00 | Southern Nazarene v East Central Tigers | W | 45-20 |
| NCAAF | 2022/09/10 23:00 | Ouachita Baptist Tigers v Southern Nazarene | L | 45-0 |
| NCAAF | 2022/09/01 23:00 | Southern Nazarene v Arkansas Monticello Boll Weevils | L | 26-40 |
| NCAAF | 2021/11/13 20:00 | Southern Nazarene v Oklahoma Baptist Bison | L | 14-42 |
| NCAAF | 2021/11/06 18:00 | Southern Nazarene v Southern Arkansas Muleriders | L | 10-31 |
| NCAAF | 2021/10/30 19:00 | Henderson State Reddies v Southern Nazarene | L | 34-3 |
| NCAAF | 2021/10/23 20:00 | Northwestern Oklahoma State Rangers v Southern Nazarene | L | 47-27 |
| NCAAF | 2021/10/14 23:00 | Southern Nazarene v Southwestern Oklahoma State Bulldogs | W | 30-22 |
| NCAAF | 2021/10/09 19:00 | Harding Bisons v Southern Nazarene | L | 49-10 |
| NCAAF | 2022/09/10 23:00 | Arkansas Tech Wonder Boys v East Central Tigers | L | 35-13 |
| NCAAF | 2022/09/01 23:00 | East Central Tigers v Harding Bisons | L | 12-29 |
| NCAAF | 2021/11/13 20:00 | Southeastern Oklahoma State Savage Storm v East Central Tigers | W | 28-30 |
| NCAAF | 2021/11/06 19:00 | Arkansas Monticello Boll Weevils v East Central Tigers | W | 10-35 |
| NCAAF | 2021/10/30 19:00 | East Central Tigers v Ouachita Baptist Tigers | L | 28-43 |
| NCAAF | 2021/10/23 19:00 | Southwestern Oklahoma State Bulldogs v East Central Tigers | W | 34-44 |
| NCAAF | 2021/10/16 23:00 | East Central Tigers v Oklahoma Baptist Bison | L | 20-47 |
| NCAAF | 2021/10/09 19:00 | Henderson State Reddies v East Central Tigers | L | 59-24 |