Stadium: Callaway Stadium Round: 1
| NCAAF | 2021/10/09 17:00 | Methodist Monarchs v Lagrange Panthers | L | 34-17 |
| NCAAF | 2019/11/09 18:00 | Methodist Monarchs v Lagrange Panthers | L | 37-33 |
| NCAAF | 2018/11/03 17:00 | Lagrange Panthers v Methodist Monarchs | W | 48-38 |
| NCAAF | 2022/09/17 17:00 | Lagrange Panthers v Ferrum Panthers | W | 44-38 |
| NCAAF | 2022/09/10 22:00 | Berry Vikings v Lagrange Panthers | L | 56-10 |
| NCAAF | 2021/11/13 18:00 | Lagrange Panthers v Huntingdon Hawks | L | 9-55 |
| NCAAF | 2021/11/06 17:00 | Averett Cougars v Lagrange Panthers | L | 31-22 |
| NCAAF | 2021/10/30 17:00 | Lagrange Panthers v Greensboro Pride | W | 29-14 |
| NCAAF | 2021/10/23 18:00 | Maryville Scots v Lagrange Panthers | L | 52-16 |
| NCAAF | 2021/10/16 20:00 | Lagrange Panthers v Brevard Tornados | L | 10-20 |
| NCAAF | 2021/10/09 17:00 | Methodist Monarchs v Lagrange Panthers | L | 34-17 |
| NCAAF | 2022/09/17 17:00 | Methodist Monarchs v Washington And Lee Generals | L | 14-37 |
| NCAAF | 2022/09/10 23:00 | Guilford Quakers v Methodist Monarchs | W | 16-49 |
| NCAAF | 2022/09/03 17:00 | Methodist Monarchs v Shenandoah Hornets | L | 10-27 |
| NCAAF | 2021/11/13 22:00 | Methodist Monarchs v Nc Wesleyan Battling Bishops | W | 38-7 |
| NCAAF | 2021/11/06 16:00 | Greensboro Pride v Methodist Monarchs | W | 14-40 |
| NCAAF | 2021/10/30 17:00 | Methodist Monarchs v Brevard Tornados | W | 31-27 |
| NCAAF | 2021/10/23 22:00 | Averett Cougars v Methodist Monarchs | W | 24-31 |
| NCAAF | 2021/10/09 17:00 | Methodist Monarchs v Lagrange Panthers | W | 34-17 |